Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-MazE
Location 1363970..1364628 Replicon chromosome
Accession NZ_CP019240
Organism Rhodoferax antarcticus strain DSMZ24876

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag RA876_RS06680 Protein ID WP_075586749.1
Coordinates 1364227..1364628 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag RA876_RS06675 Protein ID WP_075586748.1
Coordinates 1363970..1364230 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RA876_RS06655 1360568..1362037 + 1470 WP_075586745.1 DUF3375 domain-containing protein -
RA876_RS06660 1362040..1362810 + 771 WP_083633907.1 DUF4194 domain-containing protein -
RA876_RS06665 1363005..1363301 + 297 WP_075586746.1 DUF1778 domain-containing protein -
RA876_RS06670 1363308..1363829 + 522 WP_075586747.1 GNAT family N-acetyltransferase -
RA876_RS06675 1363970..1364230 + 261 WP_075586748.1 DNA-binding protein Antitoxin
RA876_RS06680 1364227..1364628 + 402 WP_075586749.1 type II toxin-antitoxin system VapC family toxin Toxin
RA876_RS20260 1364685..1364825 + 141 WP_156876214.1 hypothetical protein -
RA876_RS06685 1364822..1368355 + 3534 WP_075586750.1 ATP-binding protein -
RA876_RS19855 1368352..1369551 + 1200 Protein_1318 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-125)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14560.02 Da        Isoelectric Point: 5.5138

>T71895 WP_075586749.1 NZ_CP019240:1364227-1364628 [Rhodoferax antarcticus]
MTQRYMLDTNVVSHIMQGRDAALLALLTQVPVGQVVISSVTLAELEYGLHCKGQPVRLKNAMTQVLLHMDVLPWDESVAR
CYGVLCSTLEAQGINLSDLDMMIAAHAVAVDATLVSRDKAFAQVPAPLRLETW

Download         Length: 402 bp

>T71895 NZ_CP019240:1364227-1364628 [Rhodoferax antarcticus]
ATGACGCAGCGCTACATGCTCGACACCAACGTGGTGAGCCACATCATGCAAGGGCGCGACGCTGCTTTGCTGGCTCTTTT
AACCCAAGTGCCCGTGGGCCAAGTGGTGATTTCCAGCGTGACGCTGGCCGAGCTTGAATACGGTCTGCACTGCAAAGGGC
AACCCGTGCGCCTGAAAAACGCCATGACCCAGGTGCTGCTGCACATGGATGTGCTGCCTTGGGATGAATCCGTGGCGCGG
TGTTATGGCGTGTTGTGCAGCACGCTGGAAGCGCAGGGCATCAACCTCAGCGATCTTGACATGATGATTGCTGCCCACGC
CGTTGCGGTGGATGCCACTCTGGTCAGCCGCGACAAGGCCTTTGCCCAAGTGCCCGCGCCATTGAGGCTAGAAACTTGGT
GA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9838.16 Da        Isoelectric Point: 5.0774

>AT71895 WP_075586748.1 NZ_CP019240:1363970-1364230 [Rhodoferax antarcticus]
MQQTAKIFATGRSQAVRLPLEFRFDVAEVYIRHDPVTGDVVLSRKPTDWQGLLDAVAQNMGEDLLIERRAVATPQVRRDP
FEGWQE

Download         Length: 261 bp

>AT71895 NZ_CP019240:1363970-1364230 [Rhodoferax antarcticus]
ATGCAACAAACCGCCAAAATATTTGCCACCGGCCGCAGTCAAGCCGTTCGGCTGCCGCTGGAATTTCGCTTTGATGTGGC
AGAAGTTTATATTCGCCACGACCCTGTTACGGGCGATGTGGTGCTGTCGCGCAAGCCCACAGACTGGCAAGGCCTGCTGG
ATGCCGTCGCACAAAACATGGGTGAAGACCTGTTGATTGAGCGCCGCGCTGTGGCAACGCCCCAGGTCCGCCGCGACCCC
TTTGAGGGCTGGCAGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References