Detailed information of TA system TA071893

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): paaR-paaA-parE/RelE(toxin)
• Location: 626860..627335
• Replicon: chromosome
• Accession: NZ_CP019240
• Organism: Rhodoferax antarcticus strain DSMZ24876

Toxin (Protein)

• Gene name: parE_1
• Uniprot ID: -
• Locus tag: RA876_RS03030
• Protein ID: WP_075586120.1
• Coordinates: 626860..627141 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: paaA
• Uniprot ID: -
• Locus tag: RA876_RS03035
• Protein ID: WP_075586121.1
• Coordinates: 627141..627335 (-)
• Length: 65 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RA876_RS03020	623049..625898	-	2850	WP_075586118.1	methionine synthase	-
RA876_RS03025	626269..626532	+	264	WP_139313340.1	hypothetical protein	-
RA876_RS03030	626860..627141	-	282	WP_075586120.1	type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family	Toxin
RA876_RS03035	627141..627335	-	195	WP_075586121.1	hypothetical protein	Antitoxin
RA876_RS03045	627672..628352	-	681	WP_075586122.1	response regulator	-
RA876_RS03050	628392..630596	-	2205	WP_083633846.1	HAMP domain-containing protein	-
RA876_RS03055	630662..631300	-	639	WP_075586123.1	DUF4390 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10810.50 Da
• Isoelectric Point: 6.2051

>T71893 WP_075586120.1 NZ_CP019240:c627141-626860 [Rhodoferax antarcticus]
MLSIIWAPTADADLEEITDFIWQRNPIAAQRIWQLIQDSVLPLSDHPYLYRQSERMPGCREVVVHPNFIVVYQVGADSIK
VLRVLHARQQFPV

Nucleotide

• Length: 282 bp

>T71893 NZ_CP019240:c627141-626860 [Rhodoferax antarcticus]
ATGCTGTCCATCATCTGGGCACCTACTGCCGACGCGGATCTGGAAGAAATCACCGATTTTATTTGGCAGCGTAACCCAAT
AGCTGCACAGAGAATTTGGCAGTTGATCCAAGATAGCGTACTACCGCTCTCAGACCATCCCTACCTTTATCGCCAAAGCG
AGCGCATGCCTGGTTGTCGGGAGGTTGTGGTGCATCCTAATTTTATTGTTGTGTACCAGGTGGGAGCCGATTCGATCAAG
GTTCTTCGCGTGCTGCATGCTCGCCAGCAGTTCCCCGTTTAG

Antitoxin

Protein

• Length: 65 a.a.
• Molecular weight: 7451.25 Da
• Isoelectric Point: 4.6855

>AT71893 WP_075586121.1 NZ_CP019240:c627335-627141 [Rhodoferax antarcticus]
MNAVLSPIVSEFETQEAADSYDQWFRAKVQEALDDTRPGIPHDEVARRMQERFARLRQQSITTN

Nucleotide

• Length: 195 bp

>AT71893 NZ_CP019240:c627335-627141 [Rhodoferax antarcticus]
ATGAATGCAGTTCTGTCGCCCATCGTTTCTGAGTTTGAGACTCAGGAAGCCGCCGATAGCTATGACCAGTGGTTTCGAGC
CAAGGTTCAAGAAGCCTTGGATGACACTCGGCCAGGTATCCCACACGATGAAGTTGCTCGACGTATGCAAGAGCGTTTTG
CCAGACTGCGCCAACAAAGCATCACGACCAACTGA