Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 5662615..5663288 Replicon chromosome
Accession NZ_CP019236
Organism Rhodoferax koreense strain DCY-110

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag RD110_RS26165 Protein ID WP_076203811.1
Coordinates 5662857..5663288 (+) Length 144 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag RD110_RS26160 Protein ID WP_076203808.1
Coordinates 5662615..5662860 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RD110_RS26135 5658241..5659650 + 1410 WP_076203793.1 efflux transporter outer membrane subunit -
RD110_RS26140 5659734..5659982 + 249 WP_076203796.1 hypothetical protein -
RD110_RS26145 5660156..5660341 + 186 WP_076203799.1 CsbD family protein -
RD110_RS26150 5660401..5661153 - 753 WP_076203802.1 TerC family protein -
RD110_RS26155 5661271..5662464 - 1194 WP_083686719.1 MltA domain-containing protein -
RD110_RS28430 5662397..5662546 + 150 WP_204250094.1 hypothetical protein -
RD110_RS26160 5662615..5662860 + 246 WP_076203808.1 Arc family DNA-binding protein Antitoxin
RD110_RS26165 5662857..5663288 + 432 WP_076203811.1 type II toxin-antitoxin system VapC family toxin Toxin
RD110_RS26170 5663333..5663968 - 636 WP_076203814.1 response regulator transcription factor -
RD110_RS26175 5663993..5666032 - 2040 WP_083686720.1 PAS domain-containing sensor histidine kinase -
RD110_RS26180 5666122..5666934 - 813 WP_076203817.1 carbon-nitrogen hydrolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin

Arc-like DNA binding domain

(13-45)


Sequences

Toxin        


Download         Length: 144 a.a.        Molecular weight: 15924.11 Da        Isoelectric Point: 4.4851

>T71884 WP_076203811.1 NZ_CP019236:5662857-5663288 [Rhodoferax koreense]
MMLLDTNVLSELMRQQPDRQVLAWLDAQPTETLFVSAVTVAELMYGIERLPEGRRKDSLRETAWTMLEEDFDGRILPFDG
AAATRYAWLAAQRERSGRPIGMADAQIAAICLGTHADLATRNTKDFAGLGLVLTNPWQTASQD

Download         Length: 432 bp

>T71884 NZ_CP019236:5662857-5663288 [Rhodoferax koreense]
ATGATGCTGCTGGACACGAATGTGTTGTCCGAACTCATGCGCCAGCAGCCGGATCGCCAGGTGCTGGCCTGGCTGGACGC
CCAGCCGACCGAAACCTTGTTCGTCAGCGCGGTGACGGTGGCCGAACTCATGTACGGCATCGAGCGCCTGCCCGAGGGCC
GGCGCAAAGACAGCCTGCGTGAGACCGCGTGGACGATGTTGGAAGAGGATTTCGATGGCCGCATCCTGCCATTCGACGGC
GCGGCGGCCACTCGTTACGCATGGCTCGCGGCCCAACGGGAGCGCTCAGGTCGGCCGATCGGCATGGCCGATGCGCAGAT
CGCCGCCATCTGCCTTGGCACGCACGCCGACCTGGCGACGCGCAACACCAAGGACTTCGCCGGTCTCGGTCTTGTATTGA
CCAACCCCTGGCAGACCGCGTCCCAAGATTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8997.36 Da        Isoelectric Point: 10.7279

>AT71884 WP_076203808.1 NZ_CP019236:5662615-5662860 [Rhodoferax koreense]
MATLTIRNFDETLKQRLRIEAAEHGRSMEEEVRSILRQALEKAAPARGLGSRIHQRFAAIGGVDLELPAHTEPARAAKLK
P

Download         Length: 246 bp

>AT71884 NZ_CP019236:5662615-5662860 [Rhodoferax koreense]
ATGGCCACTTTGACCATCCGAAATTTTGACGAGACGCTGAAACAACGCCTGCGCATCGAGGCCGCCGAACATGGGCGTTC
GATGGAAGAAGAGGTTCGCTCGATTCTTCGGCAGGCACTCGAAAAAGCGGCGCCCGCACGCGGCCTCGGCAGCCGTATCC
ATCAACGTTTCGCCGCCATCGGTGGCGTCGATCTCGAGTTGCCTGCGCACACCGAACCAGCCCGAGCCGCGAAGCTGAAG
CCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References