Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 3588607..3589172 Replicon chromosome
Accession NZ_CP019236
Organism Rhodoferax koreense strain DCY-110

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag RD110_RS16665 Protein ID WP_076200507.1
Coordinates 3588607..3588978 (-) Length 124 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag RD110_RS16670 Protein ID WP_076200508.1
Coordinates 3588975..3589172 (-) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RD110_RS16645 3584059..3584847 - 789 WP_076200504.1 SDR family oxidoreductase -
RD110_RS16650 3585178..3587130 + 1953 WP_076200505.1 helix-turn-helix domain-containing protein -
RD110_RS16655 3587194..3587556 - 363 WP_076205149.1 translation initiation factor Sui1 -
RD110_RS16660 3587576..3588580 - 1005 WP_076200506.1 aldo/keto reductase -
RD110_RS16665 3588607..3588978 - 372 WP_076200507.1 type II toxin-antitoxin system VapC family toxin Toxin
RD110_RS16670 3588975..3589172 - 198 WP_076200508.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
RD110_RS16675 3589313..3589540 + 228 WP_076200509.1 hypothetical protein -
RD110_RS16680 3589570..3590838 + 1269 WP_076200510.1 DEAD/DEAH box helicase -
RD110_RS16685 3590830..3591819 - 990 WP_076200511.1 tripartite tricarboxylate transporter substrate binding protein -
RD110_RS16690 3591889..3592239 - 351 WP_076200512.1 hydroxyisourate hydrolase -
RD110_RS16695 3592318..3592989 + 672 WP_076200513.1 GntR family transcriptional regulator -
RD110_RS16700 3593168..3594142 + 975 WP_076200514.1 allantoinase PuuE -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-42)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13164.23 Da        Isoelectric Point: 7.5207

>T71883 WP_076200507.1 NZ_CP019236:c3588978-3588607 [Rhodoferax koreense]
MILVDTSVWVDHLQRGNKTLTHCLNGGQVLTHPFVIGELALGSLQQRAQVLEALQNLSQAATATDKEVLGFISTHALHGI
GIGYVDAHLLASTRLTPGATLWTLDKRLQAAALKLGLATNLLH

Download         Length: 372 bp

>T71883 NZ_CP019236:c3588978-3588607 [Rhodoferax koreense]
ATGATCCTGGTCGATACCTCGGTGTGGGTCGACCATTTGCAAAGAGGCAATAAAACCTTGACCCATTGTCTGAACGGCGG
CCAGGTGTTGACCCATCCGTTCGTCATAGGCGAACTTGCCTTGGGCAGCTTGCAGCAGCGAGCACAGGTTCTGGAAGCGT
TGCAGAATCTGTCACAAGCGGCCACGGCGACCGATAAAGAGGTGCTGGGATTCATCTCCACGCATGCGCTGCACGGCATC
GGCATCGGGTACGTGGACGCACATTTGCTCGCATCCACGCGGCTGACGCCAGGCGCGACGCTGTGGACCCTCGACAAACG
ATTGCAGGCCGCGGCGCTCAAGCTCGGCCTGGCCACCAACCTGCTGCATTGA

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7090.17 Da        Isoelectric Point: 8.8949

>AT71883 WP_076200508.1 NZ_CP019236:c3589172-3588975 [Rhodoferax koreense]
MRTTLALDDDLLATAERFTGLKEKSALVREALKALIERESARRLALLGGSEPSLEPVARRPSPTT

Download         Length: 198 bp

>AT71883 NZ_CP019236:c3589172-3588975 [Rhodoferax koreense]
ATGCGAACCACCCTTGCTCTCGATGACGATCTGCTGGCCACCGCCGAACGTTTCACCGGCCTGAAAGAAAAATCGGCGCT
GGTGCGCGAAGCGCTGAAAGCCTTGATCGAGCGCGAAAGTGCTCGCCGCCTGGCGCTGCTCGGCGGCTCCGAACCCAGCC
TCGAGCCTGTTGCTCGGCGTCCATCACCCACAACATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References