Detailed information of TA system TA071875

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2487588..2488144
• Replicon: chromosome
• Accession: NZ_CP019228
• Organism: Xanthomonas oryzae pv. oryzae strain IX-221

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: BHL62_RS11770
• Protein ID: WP_229001948.1
• Coordinates: 2487893..2488144 (+)
• Length: 84 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: BHL62_RS11765
• Protein ID: WP_011408759.1
• Coordinates: 2487588..2487866 (+)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BHL62_RS11745 (BHL62_12760)	2483232..2484554	+	1323	WP_069964865.1	3-phosphoshikimate 1-carboxyvinyltransferase	-
BHL62_RS11750 (BHL62_12765)	2484578..2484868	-	291	Protein_2242	IS5/IS1182 family transposase	-
BHL62_RS11755 (BHL62_12770)	2484958..2486142	+	1185	WP_151420524.1	IS256-like element IS1113 family transposase	-
BHL62_RS11760	2487048..2487392	+	345	WP_199285675.1	hypothetical protein	-
BHL62_RS11765 (BHL62_12780)	2487588..2487866	+	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
BHL62_RS11770 (BHL62_12785)	2487893..2488144	+	252	WP_229001948.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BHL62_RS11775 (BHL62_12790)	2488221..2488475	+	255	WP_198912806.1	hypothetical protein	-
BHL62_RS11780	2488468..2488602	+	135	WP_011051575.1	hypothetical protein	-
BHL62_RS11785 (BHL62_12795)	2488671..2488925	+	255	WP_223293127.1	hypothetical protein	-
BHL62_RS11790 (BHL62_12800)	2489142..2489261	+	120	Protein_2250	IS3 family transposase	-
BHL62_RS11795	2489230..2489358	+	129	WP_012444694.1	hypothetical protein	-
BHL62_RS11805 (BHL62_12815)	2489789..2490190	-	402	WP_011259345.1	H-NS family nucleoid-associated regulatory protein	-
BHL62_RS11810 (BHL62_12820)	2490412..2490588	+	177	Protein_2253	DUF3606 domain-containing protein	-
BHL62_RS11815 (BHL62_12830)	2490870..2491207	+	338	Protein_2254	ATP-dependent DNA ligase	-
BHL62_RS11820 (BHL62_12835)	2491283..2492374	-	1092	WP_041182166.1	ribonuclease D	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	2484940..2486142	1202

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-81)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 84 a.a.
• Molecular weight: 9603.92 Da
• Isoelectric Point: 9.9718

>T71875 WP_229001948.1 NZ_CP019228:2487893-2488144 [Xanthomonas oryzae pv. oryzae]
MLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDGDTVTILAVRHQKE
AGY

Nucleotide

• Length: 252 bp

>T71875 NZ_CP019228:2487893-2488144 [Xanthomonas oryzae pv. oryzae]
ATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGATGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGT
CCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAGAAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATT
TTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGGGATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAA
GCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT71875 WP_011408759.1 NZ_CP019228:2487588-2487866 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT71875 NZ_CP019228:2487588-2487866 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2