Detailed information of TA system TA071870

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2081033..2081589
• Replicon: chromosome
• Accession: NZ_CP019226
• Organism: Xanthomonas oryzae pv. oryzae strain IX-280

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: BCR61_RS10400
• Protein ID: WP_027703932.1
• Coordinates: 2081299..2081589 (+)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: BCR61_RS10395
• Protein ID: WP_011408759.1
• Coordinates: 2081033..2081311 (+)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BCR61_RS10365	2076150..2076755	-	606	Protein_1869	DNA-3-methyladenine glycosylase	-
BCR61_RS10370	2076857..2077822	-	966	WP_109181970.1	IS1595-like element ISXo5 family transposase	-
BCR61_RS10380	2078403..2079587	+	1185	WP_117231633.1	IS256 family transposase	-
BCR61_RS10385	2080348..2080548	+	201	WP_027703931.1	ribbon-helix-helix protein, CopG family	-
BCR61_RS25430	2080493..2080837	+	345	WP_198912817.1	hypothetical protein	-
BCR61_RS25435	2080749..2080952	+	204	WP_198912807.1	hypothetical protein	-
BCR61_RS10395	2081033..2081311	+	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
BCR61_RS10400	2081299..2081589	+	291	WP_027703932.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BCR61_RS25440	2081850..2082047	+	198	WP_004541336.1	hypothetical protein	-
BCR61_RS10410	2082191..2082370	+	180	WP_015463309.1	hypothetical protein	-
BCR61_RS10430	2083234..2083635	-	402	WP_011259345.1	H-NS histone family protein	-
BCR61_RS10435	2083857..2084033	+	177	Protein_1880	DUF3606 domain-containing protein	-
BCR61_RS25055	2084049..2084255	+	207	Protein_1881	hypothetical protein	-
BCR61_RS10445	2084315..2084652	+	338	Protein_1882	ATP-dependent DNA ligase	-
BCR61_RS10450	2084728..2085819	-	1092	WP_041182166.1	ribonuclease D	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10915.48 Da
• Isoelectric Point: 9.5554

>T71870 WP_027703932.1 NZ_CP019226:2081299-2081589 [Xanthomonas oryzae pv. oryzae]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILAVRHQKEAGY

Nucleotide

• Length: 291 bp

>T71870 NZ_CP019226:2081299-2081589 [Xanthomonas oryzae pv. oryzae]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGA
TGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGG
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT71870 WP_011408759.1 NZ_CP019226:2081033-2081311 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT71870 NZ_CP019226:2081033-2081311 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2