Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1868868..1869013 Replicon chromosome
Accession NZ_CP019219
Organism Klebsiella pneumoniae strain 1756

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1868904..1869006 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1868868..1869013 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BWG70_RS09510 1863998..1866058 + 2061 WP_077274040.1 oligopeptidase B -
BWG70_RS09520 1866062..1866721 - 660 WP_002911407.1 exodeoxyribonuclease X -
BWG70_RS09525 1866800..1867030 - 231 WP_002911406.1 DNA polymerase III subunit theta -
BWG70_RS09530 1867143..1867517 + 375 WP_004151448.1 CopC domain-containing protein YobA -
BWG70_RS09535 1867521..1868390 + 870 WP_004891049.1 copper homeostasis membrane protein CopD -
BWG70_RS09540 1868407..1868745 + 339 WP_002911404.1 YebY family protein -
- 1868868..1869013 - 146 - - Antitoxin
- 1868904..1869006 + 103 - - Toxin
BWG70_RS27710 1869381..1869524 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
BWG70_RS09555 1869629..1870597 - 969 WP_074181864.1 VirK/YbjX family protein -
BWG70_RS09560 1870754..1871407 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
BWG70_RS09565 1871404..1871595 - 192 WP_002911395.1 YebW family protein -
BWG70_RS09570 1871693..1871932 - 240 WP_002911393.1 YebV family protein -
BWG70_RS09575 1872048..1873481 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T71838 NZ_CP019219:1868904-1869006 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT71838 NZ_CP019219:c1869013-1868868 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References