Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 1865..2391 Replicon plasmid pATCC10717
Accession NZ_CP019193
Organism Salmonella enterica subsp. enterica serovar Rubislaw str. ATCC 10717

Toxin (Protein)


Gene name relE Uniprot ID A0A6W0P1Y7
Locus tag SEERU717_RS22860 Protein ID WP_023208109.1
Coordinates 1865..2152 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID S1F6D3
Locus tag SEERU717_RS22865 Protein ID WP_000534858.1
Coordinates 2152..2391 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SEERU717_RS22845 271..1011 - 741 WP_023208106.1 site-specific integrase -
SEERU717_RS22855 1376..1671 - 296 Protein_1 type II toxin-antitoxin system RelE/ParE family toxin -
SEERU717_RS22860 1865..2152 - 288 WP_023208109.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
SEERU717_RS22865 2152..2391 - 240 WP_000534858.1 type II toxin-antitoxin system antitoxin RelB Antitoxin
SEERU717_RS22875 3084..3464 + 381 Protein_4 hypothetical protein -
SEERU717_RS24745 3932..4408 + 477 WP_078048702.1 hypothetical protein -
SEERU717_RS22890 4617..5429 + 813 WP_023207898.1 helix-turn-helix domain-containing protein -
SEERU717_RS22895 5825..6340 - 516 WP_023207897.1 CaiF/GrlA family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..196866 196866


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-122)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 14146.97 Da        Isoelectric Point: 5.5500

>T71824 WP_023208109.1 NZ_CP019193:c2152-1865 [Salmonella enterica subsp. enterica serovar Rubislaw str. ATCC]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFF

Download         Length: 288 bp

>T71824 NZ_CP019193:c2152-1865 [Salmonella enterica subsp. enterica serovar Rubislaw str. ATCC]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 11792.14 Da        Isoelectric Point: 5.5500

>AT71824 WP_000534858.1 NZ_CP019193:c2391-2152 [Salmonella enterica subsp. enterica serovar Rubislaw str. ATCC]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Download         Length: 240 bp

>AT71824 NZ_CP019193:c2391-2152 [Salmonella enterica subsp. enterica serovar Rubislaw str. ATCC]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6W0P1Y7

Antitoxin

Source ID Structure
PDB 4FXE
PDB 2KC8
PDB 2K29
AlphaFold DB A0A4V1CTS8

References