Detailed information of TA system TA071822

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vagCD/VapC-VagC
• Location: 162359..163002
• Replicon: plasmid pATCCBAA1673_01
• Accession: NZ_CP019190
• Organism: Salmonella enterica subsp. enterica serovar Poona str. ATCC BAA-1673

Toxin (Protein)

• Gene name: vagD
• Uniprot ID: -
• Locus tag: SEEP1673_RS26280
• Protein ID: WP_023213230.1
• Coordinates: 162359..162775 (-)
• Length: 139 a.a.

Antitoxin (Protein)

• Gene name: vagC
• Uniprot ID: -
• Locus tag: SEEP1673_RS26285
• Protein ID: WP_023213231.1
• Coordinates: 162772..163002 (-)
• Length: 77 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SEEP1673_RS26250	157475..158167	-	693	WP_024160651.1	molecular chaperone	-
SEEP1673_RS26255	158295..158837	-	543	WP_080092450.1	type 1 fimbrial protein	-
SEEP1673_RS26260	158910..159446	-	537	WP_023213765.1	type 1 fimbrial protein	-
SEEP1673_RS26265	159766..160422	-	657	WP_071646393.1	tyrosine-type recombinase/integrase	-
SEEP1673_RS26270	160595..161671	-	1077	Protein_177	ISKra4 family transposase	-
SEEP1673_RS27000	161687..161893	-	207	Protein_178	plasmid pRiA4b ORF-3 family protein	-
SEEP1673_RS26280	162359..162775	-	417	WP_023213230.1	type II toxin-antitoxin system VapC family toxin	Toxin
SEEP1673_RS26285	162772..163002	-	231	WP_023213231.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
SEEP1673_RS26300	163754..163972	+	219	WP_023213232.1	type II toxin-antitoxin system antitoxin CcdA	-
SEEP1673_RS26305	163974..164279	+	306	WP_023213233.1	type II toxin-antitoxin system toxin CcdB	-
SEEP1673_RS26310	164281..164562	+	282	WP_023213234.1	hypothetical protein	-
SEEP1673_RS26315	164659..165093	+	435	WP_023213235.1	hypothetical protein	-
SEEP1673_RS26320	165090..165872	+	783	WP_023213236.1	site-specific integrase	-
SEEP1673_RS26325	166016..166747	-	732	Protein_186	Rpn family recombination-promoting nuclease/putative transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..186451	186451

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (4-120)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-53)

Sequences

Toxin

Protein

• Length: 139 a.a.
• Molecular weight: 20475.56 Da
• Isoelectric Point: 5.5500

>T71822 WP_023213230.1 NZ_CP019190:c162775-162359 [Salmonella enterica subsp. enterica serovar Poona str. ATCC]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 417 bp

>T71822 NZ_CP019190:c162775-162359 [Salmonella enterica subsp. enterica serovar Poona str. ATCC]
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Antitoxin

Protein

• Length: 77 a.a.
• Molecular weight: 11350.61 Da
• Isoelectric Point: 5.5500

>AT71822 WP_023213231.1 NZ_CP019190:c163002-162772 [Salmonella enterica subsp. enterica serovar Poona str. ATCC]
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Nucleotide

• Length: 231 bp

>AT71822 NZ_CP019190:c163002-162772 [Salmonella enterica subsp. enterica serovar Poona str. ATCC]
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