Detailed information of TA system TA071821

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ccdAB/CcdA(antitoxin)
• Location: 145806..146359
• Replicon: plasmid pATCCBAA1673_01
• Accession: NZ_CP019190
• Organism: Salmonella enterica subsp. enterica serovar Poona str. ATCC BAA-1673

Toxin (Protein)

• Gene name: ccdB
• Uniprot ID: -
• Locus tag: SEEP1673_RS26180
• Protein ID: WP_023214121.1
• Coordinates: 145806..146120 (-)
• Length: 105 a.a.

Antitoxin (Protein)

• Gene name: ccdA
• Uniprot ID: A0A730HTS6
• Locus tag: SEEP1673_RS26185
• Protein ID: WP_023214120.1
• Coordinates: 146123..146359 (-)
• Length: 79 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SEEP1673_RS26160	143141..143401	-	261	WP_071646364.1	hypothetical protein	-
SEEP1673_RS26165	143385..144014	-	630	WP_079932843.1	LuxR C-terminal-related transcriptional regulator	-
SEEP1673_RS26170	144011..144484	-	474	WP_102035459.1	CaiF/GrlA family transcriptional regulator	-
SEEP1673_RS26175	144809..145588	-	780	WP_080092426.1	tyrosine-type recombinase/integrase	-
SEEP1673_RS26180	145806..146120	-	315	WP_023214121.1	CcdB family protein	Toxin
SEEP1673_RS26185	146123..146359	-	237	WP_023214120.1	type II toxin-antitoxin system CcdA family antitoxin	Antitoxin
SEEP1673_RS26850	147109..147276	-	168	WP_157934966.1	hypothetical protein	-
SEEP1673_RS26200	147302..147805	-	504	WP_023214117.1	CaiF/GrlA family transcriptional regulator	-
SEEP1673_RS26205	147816..148430	-	615	WP_071645911.1	LuxR C-terminal-related transcriptional regulator	-
SEEP1673_RS26210	148427..148939	-	513	WP_080092427.1	CaiF/GrlA family transcriptional regulator	-
SEEP1673_RS26215	148961..150235	-	1275	WP_023214168.1	FKBP-type peptidyl-prolyl cis-trans isomerase	-
SEEP1673_RS26220	150296..151129	-	834	WP_023214169.1	sel1 repeat family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..186451	186451

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (6-85)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (2-72)

Sequences

Toxin

Protein

• Length: 105 a.a.
• Molecular weight: 15471.56 Da
• Isoelectric Point: 5.5500

>T71821 WP_023214121.1 NZ_CP019190:c146120-145806 [Salmonella enterica subsp. enterica serovar Poona str. ATCC]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 315 bp

>T71821 NZ_CP019190:c146120-145806 [Salmonella enterica subsp. enterica serovar Poona str. ATCC]
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Antitoxin

Protein

• Length: 79 a.a.
• Molecular weight: 11644.97 Da
• Isoelectric Point: 5.5500

>AT71821 WP_023214120.1 NZ_CP019190:c146359-146123 [Salmonella enterica subsp. enterica serovar Poona str. ATCC]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 237 bp

>AT71821 NZ_CP019190:c146359-146123 [Salmonella enterica subsp. enterica serovar Poona str. ATCC]
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Structures

Antitoxin

• AlphaFold DB: A0A730HTS6