Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 106118..106649 Replicon plasmid pATCCBAA1673_01
Accession NZ_CP019190
Organism Salmonella enterica subsp. enterica serovar Poona str. ATCC BAA-1673

Toxin (Protein)


Gene name relE Uniprot ID A0A5T4YFZ3
Locus tag SEEP1673_RS25975 Protein ID WP_023214316.1
Coordinates 106118..106408 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A5T7VUE7
Locus tag SEEP1673_RS25980 Protein ID WP_023214317.1
Coordinates 106398..106649 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SEEP1673_RS25965 104251..105369 - 1119 WP_102035462.1 hypothetical protein -
SEEP1673_RS25970 105848..105976 + 129 WP_157934967.1 hypothetical protein -
SEEP1673_RS25975 106118..106408 - 291 WP_023214316.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
SEEP1673_RS25980 106398..106649 - 252 WP_023214317.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
SEEP1673_RS25985 106887..107186 + 300 WP_023214318.1 hypothetical protein -
SEEP1673_RS25990 107406..108425 - 1020 WP_023214319.1 IS110 family transposase -
SEEP1673_RS26985 108507..108812 - 306 WP_023214320.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..186451 186451


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-103)

Antitoxin

HigA2-like, helix-turn-helix domain

(35-98)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 14294.15 Da        Isoelectric Point: 5.5500

>T71819 WP_023214316.1 NZ_CP019190:c106408-106118 [Salmonella enterica subsp. enterica serovar Poona str. ATCC]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFF

Download         Length: 291 bp

>T71819 NZ_CP019190:c106408-106118 [Salmonella enterica subsp. enterica serovar Poona str. ATCC]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
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Antitoxin


Download         Length: 84 a.a.        Molecular weight: 12380.85 Da        Isoelectric Point: 5.5500

>AT71819 WP_023214317.1 NZ_CP019190:c106649-106398 [Salmonella enterica subsp. enterica serovar Poona str. ATCC]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFF

Download         Length: 252 bp

>AT71819 NZ_CP019190:c106649-106398 [Salmonella enterica subsp. enterica serovar Poona str. ATCC]
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TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
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Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5T4YFZ3

Antitoxin

Source ID Structure
AlphaFold DB A0A5T7VUE7

References