Detailed information of TA system TA071816

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 35113..35738
• Replicon: plasmid pATCCBAA1673_01
• Accession: NZ_CP019190
• Organism: Salmonella enterica subsp. enterica serovar Poona str. ATCC BAA-1673

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: SEEP1673_RS25590
• Protein ID: WP_023213439.1
• Coordinates: 35113..35511 (-)
• Length: 133 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: SEEP1673_RS25595
• Protein ID: WP_023213438.1
• Coordinates: 35511..35738 (-)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SEEP1673_RS25575	31438..31935	+	498	WP_024160591.1	surface exclusion protein	-
SEEP1673_RS25580	31967..32698	+	732	WP_000850424.1	complement resistance protein TraT	-
SEEP1673_RS25585	32951..35104	+	2154	WP_023213440.1	type IV conjugative transfer system coupling protein TraD	-
SEEP1673_RS25590	35113..35511	-	399	WP_023213439.1	tRNA(fMet)-specific endonuclease VapC	Toxin
SEEP1673_RS25595	35511..35738	-	228	WP_023213438.1	toxin-antitoxin system antitoxin VapB	Antitoxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..186451	186451

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (4-119)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (2-46)

Sequences

Toxin

Protein

• Length: 133 a.a.
• Molecular weight: 19592.50 Da
• Isoelectric Point: 5.5500

>T71816 WP_023213439.1 NZ_CP019190:c35511-35113 [Salmonella enterica subsp. enterica serovar Poona str. ATCC]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
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Nucleotide

• Length: 399 bp

>T71816 NZ_CP019190:c35511-35113 [Salmonella enterica subsp. enterica serovar Poona str. ATCC]
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Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 11203.44 Da
• Isoelectric Point: 5.5500

>AT71816 WP_023213438.1 NZ_CP019190:c35738-35511 [Salmonella enterica subsp. enterica serovar Poona str. ATCC]
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Nucleotide

• Length: 228 bp

>AT71816 NZ_CP019190:c35738-35511 [Salmonella enterica subsp. enterica serovar Poona str. ATCC]
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