Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | phd-doc/Doc-Phd |
| Location | 66305..66906 | Replicon | plasmid pATCC10729_02 |
| Accession | NZ_CP019188 | ||
| Organism | Salmonella enterica subsp. enterica serovar Pomona str. ATCC 10729 | ||
Toxin (Protein)
| Gene name | doc | Uniprot ID | U9YA20 |
| Locus tag | SEEPO729_RS23825 | Protein ID | WP_001216045.1 |
| Coordinates | 66526..66906 (+) | Length | 127 a.a. |
Antitoxin (Protein)
| Gene name | phd | Uniprot ID | U9YQH9 |
| Locus tag | SEEPO729_RS23820 | Protein ID | WP_001190712.1 |
| Coordinates | 66305..66526 (+) | Length | 74 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SEEPO729_RS23775 | 62075..62308 | + | 234 | WP_000516536.1 | hypothetical protein | - |
| SEEPO729_RS23780 | 62487..62780 | + | 294 | WP_000269002.1 | hypothetical protein | - |
| SEEPO729_RS23785 | 62787..63161 | + | 375 | WP_000988654.1 | hypothetical protein | - |
| SEEPO729_RS23790 | 63143..63817 | + | 675 | WP_000057458.1 | hypothetical protein | - |
| SEEPO729_RS23795 | 63814..64176 | + | 363 | WP_001261545.1 | hypothetical protein | - |
| SEEPO729_RS23805 | 64838..65089 | + | 252 | WP_001667237.1 | DNA polymerase III subunit theta | - |
| SEEPO729_RS23810 | 65096..65668 | - | 573 | WP_001133670.1 | hypothetical protein | - |
| SEEPO729_RS23815 | 65843..66232 | + | 390 | WP_000506724.1 | DNA repair protein | - |
| SEEPO729_RS23820 | 66305..66526 | + | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| SEEPO729_RS23825 | 66526..66906 | + | 381 | WP_001216045.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin |
| SEEPO729_RS23830 | 66911..67090 | + | 180 | WP_000113018.1 | hypothetical protein | - |
| SEEPO729_RS23835 | 67118..68161 | + | 1044 | WP_000648834.1 | DUF968 domain-containing protein | - |
| SEEPO729_RS23840 | 68250..68702 | + | 453 | WP_001326849.1 | late promoter-activating protein | - |
| SEEPO729_RS23845 | 68788..69981 | + | 1194 | WP_000219618.1 | hypothetical protein | - |
| SEEPO729_RS23850 | 69981..71465 | + | 1485 | WP_000124159.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..95279 | 95279 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 127 a.a. Molecular weight: 16296.13 Da Isoelectric Point: 12.9004
>T71815 WP_001216045.1 NZ_CP019188:66526-66906 [Salmonella enterica subsp. enterica serovar Pomona str. ATCC 10729]
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Download Length: 381 bp
>T71815 NZ_CP019188:66526-66906 [Salmonella enterica subsp. enterica serovar Pomona str. ATCC 10729]
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Antitoxin
Download Length: 74 a.a. Molecular weight: 9502.90 Da Isoelectric Point: 12.6633
>AT71815 WP_001190712.1 NZ_CP019188:66305-66526 [Salmonella enterica subsp. enterica serovar Pomona str. ATCC 10729]
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Download Length: 222 bp
>AT71815 NZ_CP019188:66305-66526 [Salmonella enterica subsp. enterica serovar Pomona str. ATCC 10729]
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Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A829CLP7 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A829CJB6 |