Detailed information of TA system TA071809

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PP_4151-4152/excise(antitoxin)
• Location: 70410..71446
• Replicon: plasmid pCFSAN024229
• Accession: NZ_CP019175
• Organism: Salmonella enterica subsp. enterica serovar Give strain CFSAN024229

Toxin (Protein)

• Gene name: PP_4152
• Uniprot ID: -
• Locus tag: LM70_RS25320
• Protein ID: WP_031233190.1
• Coordinates: 70410..70985 (-)
• Length: 192 a.a.

Antitoxin (Protein)

• Gene name: PP_4151
• Uniprot ID: A0A2A6D4K4
• Locus tag: LM70_RS25325
• Protein ID: WP_023972447.1
• Coordinates: 70985..71446 (-)
• Length: 154 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LM70_RS25295	65652..67025	-	1374	WP_023972442.1	RES family NAD+ phosphorylase	-
LM70_RS25780	67075..67398	-	324	WP_023972443.1	hypothetical protein	-
LM70_RS25305	67395..67832	-	438	WP_000843283.1	hypothetical protein	-
LM70_RS25310	67832..68863	-	1032	WP_023972444.1	ParB/RepB/Spo0J family partition protein	-
LM70_RS25315	68863..69729	-	867	WP_023972445.1	AAA family ATPase	-
LM70_RS25320	70410..70985	-	576	WP_031233190.1	PIN domain-containing protein	Toxin
LM70_RS25325	70985..71446	-	462	WP_023972447.1	helix-turn-helix domain-containing protein	Antitoxin
LM70_RS25335	71755..72531	-	777	Protein_81	phage integrase family protein	-
LM70_RS25340	72528..73235	-	708	WP_023972450.1	hypothetical protein	-
LM70_RS25665	73279..73593	-	315	WP_139148288.1	hypothetical protein	-
LM70_RS25350	74168..74398	+	231	WP_023972452.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	-
LM70_RS25355	74395..74823	+	429	WP_023972453.1	PIN domain-containing protein	-
LM70_RS25360	74864..75742	-	879	WP_023972454.1	restriction endonuclease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..94727	94727

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-125)

Antitoxin

• Ribbon-helix-helix protein, CopG (11-49)

Sequences

Toxin

Protein

• Length: 192 a.a.
• Molecular weight: 28275.92 Da
• Isoelectric Point: 5.5500

>T71809 WP_031233190.1 NZ_CP019175:c70985-70410 [Salmonella enterica subsp. enterica serovar Give]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 576 bp

>T71809 NZ_CP019175:c70985-70410 [Salmonella enterica subsp. enterica serovar Give]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTT

Antitoxin

Protein

• Length: 154 a.a.
• Molecular weight: 22683.21 Da
• Isoelectric Point: 5.5500

>AT71809 WP_023972447.1 NZ_CP019175:c71446-70985 [Salmonella enterica subsp. enterica serovar Give]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 462 bp

>AT71809 NZ_CP019175:c71446-70985 [Salmonella enterica subsp. enterica serovar Give]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Structures

Antitoxin

• AlphaFold DB: A0A2A6D4K4