Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3373744..3373889 Replicon chromosome
Accession NZ_CP019160
Organism Klebsiella pneumoniae strain GN-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3373751..3373853 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3373744..3373889 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BKY56_RS16945 3369275..3370708 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
BKY56_RS16950 3370824..3371063 + 240 WP_002911393.1 YebV family protein -
BKY56_RS16955 3371161..3371352 + 192 WP_002911395.1 YebW family protein -
BKY56_RS16960 3371349..3372002 - 654 WP_023280291.1 protein-serine/threonine phosphatase -
BKY56_RS16965 3372159..3373127 + 969 WP_014907334.1 VirK/YbjX family protein -
BKY56_RS28495 3373232..3373375 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3373744..3373889 + 146 - - Antitoxin
- 3373751..3373853 - 103 - - Toxin
BKY56_RS16975 3374012..3374350 - 339 WP_075647430.1 YebY family protein -
BKY56_RS16980 3374367..3375236 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
BKY56_RS16985 3375240..3375614 - 375 WP_004151448.1 CopC domain-containing protein YobA -
BKY56_RS16990 3375727..3375957 + 231 WP_002911406.1 DNA polymerase III subunit theta -
BKY56_RS16995 3376036..3376695 + 660 WP_002911407.1 exodeoxyribonuclease X -
BKY56_RS17000 3376699..3378759 - 2061 WP_077273935.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T71782 NZ_CP019160:c3373853-3373751 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT71782 NZ_CP019160:3373744-3373889 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References