Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 409283..409842 Replicon chromosome
Accession NZ_CP019122
Organism Vibrio vulnificus strain FORC_054

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FORC54_RS18495 Protein ID WP_045594922.1
Coordinates 409564..409842 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FORC54_RS18490 Protein ID WP_101959291.1
Coordinates 409283..409567 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FORC54_RS18455 405118..405909 + 792 WP_101959288.1 DUF4376 domain-containing protein -
FORC54_RS18460 405906..406172 + 267 WP_101959289.1 hypothetical protein -
FORC54_RS18465 406224..406601 - 378 WP_101959290.1 hypothetical protein -
FORC54_RS18470 406878..407033 + 156 WP_080960526.1 L-threonine 3-dehydrogenase -
FORC54_RS18475 407113..407613 - 501 WP_080527077.1 hypothetical protein -
FORC54_RS18480 407691..407954 - 264 WP_017791548.1 hypothetical protein -
FORC54_RS18485 408194..409003 - 810 WP_039452822.1 SUMF1/EgtB/PvdO family nonheme iron enzyme -
FORC54_RS18490 409283..409567 + 285 WP_101959291.1 damage-inducible protein J Antitoxin
FORC54_RS18495 409564..409842 + 279 WP_045594922.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FORC54_RS18500 409871..409964 - 94 Protein_336 DUF3265 domain-containing protein -
FORC54_RS18505 410284..410538 - 255 Protein_337 hypothetical protein -
FORC54_RS18510 410643..410918 - 276 WP_158636639.1 hypothetical protein -
FORC54_RS18515 411176..411328 - 153 WP_101959712.1 DUF3265 domain-containing protein -
FORC54_RS18520 411325..411750 - 426 WP_017420108.1 hypothetical protein -
FORC54_RS18525 413312..413827 - 516 WP_101959293.1 lipocalin family protein -
FORC54_RS18530 414045..414773 - 729 WP_086467932.1 MipA/OmpV family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 353658..438244 84586


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10919.63 Da        Isoelectric Point: 4.3430

>T71775 WP_045594922.1 NZ_CP019122:409564-409842 [Vibrio vulnificus]
MILWEEESLNDREKIFEFLYDFNPDAAEKTDNLIEAKVENLLEQPLMGVQRDGIRCRLLIIPEISMVISYWVEGDIIRVL
RVLHQKQKFPTD

Download         Length: 279 bp

>T71775 NZ_CP019122:409564-409842 [Vibrio vulnificus]
ATGATTTTATGGGAAGAAGAGTCACTTAATGATCGTGAAAAGATCTTCGAGTTTCTCTATGACTTCAACCCTGATGCGGC
AGAAAAAACTGACAACCTCATTGAAGCAAAAGTAGAAAACTTGCTTGAACAACCTTTAATGGGTGTACAACGAGATGGCA
TCCGCTGTCGATTGCTCATTATTCCTGAGATTTCGATGGTTATCTCTTACTGGGTCGAGGGCGATATCATCCGAGTTTTG
CGTGTCCTCCACCAGAAACAAAAATTCCCTACGGATTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 11093.51 Da        Isoelectric Point: 9.2167

>AT71775 WP_101959291.1 NZ_CP019122:409283-409567 [Vibrio vulnificus]
MDTRIQFRVDEETKRLAQQMAESQGRILSDACRELTEQLAEQQRKILSHDAWLTEQVNLAFEKFDSGKSVFVEHQTAKSR
MEERKARIRNRGKQ

Download         Length: 285 bp

>AT71775 NZ_CP019122:409283-409567 [Vibrio vulnificus]
ATGGACACTAGAATTCAATTTCGTGTTGATGAAGAAACAAAACGCCTAGCTCAACAAATGGCTGAAAGCCAAGGTCGAAT
TCTAAGTGATGCTTGCCGTGAACTTACTGAGCAACTCGCTGAACAACAAAGAAAAATATTATCTCACGATGCATGGCTAA
CTGAACAAGTAAACCTAGCATTTGAGAAGTTTGACTCAGGAAAATCCGTTTTCGTTGAGCACCAAACTGCTAAGTCTCGA
ATGGAAGAGCGCAAAGCCAGAATCCGCAATCGAGGTAAGCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References