Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3458069..3458710 Replicon chromosome
Accession NZ_CP019114
Organism Acinetobacter baumannii strain MDR-CQ

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag BV884_RS16570 Protein ID WP_000607077.1
Coordinates 3458069..3458458 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag BV884_RS16575 Protein ID WP_011860336.1
Coordinates 3458465..3458710 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BV884_RS16555 3453187..3455382 - 2196 WP_001158906.1 TRAP transporter large permease subunit -
BV884_RS16560 3455570..3456136 - 567 WP_000651538.1 rhombosortase -
BV884_RS16565 3456214..3457299 - 1086 WP_000049106.1 hypothetical protein -
BV884_RS16570 3458069..3458458 - 390 WP_000607077.1 membrane protein Toxin
BV884_RS16575 3458465..3458710 - 246 WP_011860336.1 succinate dehydrogenase assembly factor 2 Antitoxin
BV884_RS16580 3458910..3460082 + 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
BV884_RS16585 3460131..3461621 - 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
BV884_RS16590 3461803..3462180 - 378 WP_001216380.1 50S ribosomal protein L17 -
BV884_RS16595 3462199..3463206 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(6-78)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T71751 WP_000607077.1 NZ_CP019114:c3458458-3458069 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

>T71751 NZ_CP019114:c3458458-3458069 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATAAGTCACAGAACACCGTT
TCTCGCGTCAAAATTTTAAAAATAATTGATTGTCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9842.27 Da        Isoelectric Point: 4.9001

>AT71751 WP_011860336.1 NZ_CP019114:c3458710-3458465 [Acinetobacter baumannii]
MTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLKHYVH
G

Download         Length: 246 bp

>AT71751 NZ_CP019114:c3458710-3458465 [Acinetobacter baumannii]
ATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTTTGACCCTTATGT
GAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAGACCCTGATTTAC
TAGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAACACTATGTTCAT
GGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References