Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) KacT-ataR/DUF1778(antitoxin)
Location 3278947..3279740 Replicon chromosome
Accession NZ_CP019113
Organism Enterobacter sp. SA187

Toxin (Protein)


Gene name KacT Uniprot ID -
Locus tag BMF08_RS15735 Protein ID WP_083580917.1
Coordinates 3279333..3279740 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag BMF08_RS15730 Protein ID WP_072568484.1
Coordinates 3278947..3279237 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BMF08_RS15715 3274937..3276649 + 1713 WP_072568481.1 ATP-binding cassette domain-containing protein -
BMF08_RS15720 3276842..3276979 + 138 WP_072568482.1 stationary-phase-induced ribosome-associated protein -
BMF08_RS15725 3277159..3278856 + 1698 WP_072568483.1 NAD-dependent malic enzyme -
BMF08_RS15730 3278947..3279237 + 291 WP_072568484.1 DUF1778 domain-containing protein Antitoxin
BMF08_RS15735 3279333..3279740 + 408 WP_083580917.1 GNAT family N-acetyltransferase Toxin
BMF08_RS15740 3279806..3280687 + 882 WP_072568485.1 aromatic amino acid DMT transporter YddG -
BMF08_RS15745 3280684..3282180 - 1497 WP_072568486.1 SmvA family efflux MFS transporter -
BMF08_RS15750 3282293..3282871 + 579 WP_072568487.1 TetR family transcriptional regulator -
BMF08_RS15755 3282883..3283719 - 837 WP_072568488.1 arylamine N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(19-115)

Antitoxin

Vibrio phage ICP1, Orf50

(8-84)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15592.22 Da        Isoelectric Point: 10.0182

>T71741 WP_083580917.1 NZ_CP019113:3279333-3279740 [Enterobacter sp. SA187]
MSVQQERRILRCYVLVTNEAVPEIMGFYTLSGASYEKQHLSGSQQRKLPYRNLPCVLLGRMAVDRRLQRRGFGEKLLFDA
LRRTWLTAGMVGIYALFVEAKDEAAVKFYQSLGFTLSKSQPLTLFYPVNQFEFLI

Download         Length: 408 bp

>T71741 NZ_CP019113:3279333-3279740 [Enterobacter sp. SA187]
ATGTCTGTTCAGCAAGAGCGACGTATTCTGCGTTGCTACGTGCTGGTCACAAACGAAGCCGTTCCTGAAATTATGGGATT
TTATACCCTCTCGGGGGCTTCATATGAAAAACAGCACCTTTCCGGATCCCAGCAACGCAAACTACCTTATCGTAACCTGC
CCTGTGTTCTGCTTGGCAGAATGGCGGTTGATCGACGCCTGCAACGACGGGGTTTCGGTGAGAAATTATTGTTTGATGCC
CTACGCCGCACCTGGTTAACCGCGGGCATGGTCGGCATCTATGCGCTTTTCGTCGAAGCCAAAGACGAGGCCGCCGTAAA
ATTTTATCAGTCATTAGGCTTCACGCTTTCAAAATCGCAGCCGTTAACGCTCTTCTACCCCGTTAATCAGTTCGAATTTT
TAATCTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11367.86 Da        Isoelectric Point: 6.2346

>AT71741 WP_072568484.1 NZ_CP019113:3278947-3279237 [Enterobacter sp. SA187]
MSTAKKERFDFRLDESLKKQMEEAASLLSIPVSTFVIDAVRERAAEVINEHRRIVLDEQNWERIQTLLDNPPQPTERMKA
MAAHYHDKDSWTWQKN

Download         Length: 291 bp

>AT71741 NZ_CP019113:3278947-3279237 [Enterobacter sp. SA187]
ATGTCCACCGCGAAAAAAGAACGCTTTGATTTCCGGCTTGATGAAAGTCTGAAAAAACAAATGGAAGAAGCCGCCAGCCT
GCTAAGCATACCAGTCAGTACTTTTGTGATCGATGCGGTGCGGGAGCGGGCAGCAGAAGTTATTAATGAGCACCGGCGTA
TCGTGCTGGATGAGCAAAACTGGGAGCGCATTCAGACCTTGCTGGACAATCCCCCACAGCCAACGGAACGCATGAAAGCA
ATGGCTGCACATTATCATGACAAAGACAGCTGGACGTGGCAGAAGAATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References