Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 1553659..1554260 Replicon chromosome
Accession NZ_CP019113
Organism Enterobacter sp. SA187

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag BMF08_RS07440 Protein ID WP_072570230.1
Coordinates 1553659..1554015 (-) Length 119 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag BMF08_RS07445 Protein ID WP_072570231.1
Coordinates 1554009..1554260 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BMF08_RS07425 1549230..1549844 - 615 WP_072570227.1 DUF2238 domain-containing protein -
BMF08_RS07430 1549942..1552614 - 2673 WP_072570228.1 autotransporter outer membrane beta-barrel domain-containing protein -
BMF08_RS07435 1552814..1553653 + 840 WP_072570229.1 alpha/beta hydrolase -
BMF08_RS07440 1553659..1554015 - 357 WP_072570230.1 type II toxin-antitoxin system ChpB family toxin Toxin
BMF08_RS07445 1554009..1554260 - 252 WP_072570231.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
BMF08_RS07450 1554711..1555139 + 429 WP_072570232.1 hypothetical protein -
BMF08_RS07455 1555293..1555529 + 237 WP_072570233.1 hypothetical protein -
BMF08_RS07465 1555947..1556792 + 846 WP_072570234.1 AraC family transcriptional regulator -
BMF08_RS07470 1556861..1557430 + 570 WP_199775956.1 LysE family translocator -
BMF08_RS07475 1557433..1558008 - 576 WP_072570236.1 transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(9-110)

Antitoxin

SpoVT-AbrB domain

(6-49)


Sequences

Toxin        


Download         Length: 119 a.a.        Molecular weight: 12931.85 Da        Isoelectric Point: 8.6585

>T71736 WP_072570230.1 NZ_CP019113:c1554015-1553659 [Enterobacter sp. SA187]
MVKRKQGWQRGDIVMVDFNPAVGSEQREPRPALILTKKLFNDLGMAFVAPVTQGGNYARHAGFTVSLSGSGSKTQGVVLL
NQARMIDLNARDARFVEVLDEAVVNDVLLRFSTLVEAD

Download         Length: 357 bp

>T71736 NZ_CP019113:c1554015-1553659 [Enterobacter sp. SA187]
ATGGTAAAGCGTAAGCAGGGATGGCAGCGCGGCGATATAGTCATGGTTGATTTTAATCCTGCTGTTGGCAGCGAACAGCG
GGAACCACGTCCGGCATTGATTCTTACGAAAAAACTGTTTAACGATTTGGGCATGGCGTTCGTCGCACCGGTTACTCAGG
GCGGTAATTATGCCCGTCATGCCGGGTTTACCGTTTCGCTTTCCGGCTCTGGCAGTAAAACGCAGGGGGTGGTTCTTCTC
AATCAGGCCCGGATGATTGATCTCAACGCCCGCGACGCCCGGTTTGTTGAAGTCCTGGACGAAGCCGTTGTTAACGATGT
TCTGCTCAGATTCTCCACCCTCGTCGAAGCAGATTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 8932.18 Da        Isoelectric Point: 4.3021

>AT71736 WP_072570231.1 NZ_CP019113:c1554260-1554009 [Enterobacter sp. SA187]
MSIAIKKWGNSNGVILPALLLRQLGVSAGQSLDAEVRDGALILTPVRQRYTLEELVAQCDASAPATSEEEIWGKDAPVGN
EIW

Download         Length: 252 bp

>AT71736 NZ_CP019113:c1554260-1554009 [Enterobacter sp. SA187]
ATGAGCATTGCAATCAAAAAATGGGGAAACAGTAATGGCGTTATCCTTCCCGCCCTGCTTCTCAGGCAACTGGGTGTCAG
CGCTGGTCAGTCTCTGGATGCAGAAGTCCGGGACGGCGCGCTTATTCTGACGCCAGTACGTCAACGCTATACGCTTGAAG
AACTGGTCGCACAGTGCGATGCCAGCGCACCAGCAACCAGCGAAGAAGAAATATGGGGTAAGGATGCGCCAGTGGGGAAT
GAAATATGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References