Detailed information of TA system TA071729

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mazEF/PRK09907-MazE
• Location: 1757316..1757893
• Replicon: chromosome
• Accession: NZ_CP019092
• Organism: Xanthomonas oryzae pv. oryzae strain MAI145

Toxin (Protein)

• Gene name: mazF
• Uniprot ID: -
• Locus tag: BVV13_RS08815
• Protein ID: WP_082324282.1
• Coordinates: 1757552..1757893 (+)
• Length: 114 a.a.

Antitoxin (Protein)

• Gene name: mazE
• Uniprot ID: A0A411Y3T7
• Locus tag: BVV13_RS08810
• Protein ID: WP_017154976.1
• Coordinates: 1757316..1757558 (+)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BVV13_RS08790	1753478..1754062	-	585	WP_024743447.1	NAD(P)H-dependent oxidoreductase	-
BVV13_RS08795	1754162..1755178	+	1017	WP_024743446.1	LysR family transcriptional regulator	-
BVV13_RS08805	1755730..1757220	+	1491	WP_033003336.1	site-specific integrase	-
BVV13_RS08810	1757316..1757558	+	243	WP_017154976.1	hypothetical protein	Antitoxin
BVV13_RS08815	1757552..1757893	+	342	WP_082324282.1	type II toxin-antitoxin system PemK/MazF family toxin	Toxin
BVV13_RS08820	1758015..1758380	+	366	Protein_1599	transposase	-
BVV13_RS08825	1758446..1759547	+	1102	WP_107490965.1	IS3 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (10-110)

Antitoxin

• Antitoxin PemI-like (4-76)

Sequences

Toxin

Protein

• Length: 114 a.a.
• Molecular weight: 12461.20 Da
• Isoelectric Point: 9.1473

>T71729 WP_082324282.1 NZ_CP019092:1757552-1757893 [Xanthomonas oryzae pv. oryzae]
MVNPGWVPRRSEIIHLDDVGGAGHEQRGDRPHLVLSSQGYNDTTSLVVCVPVTTKPKGNPFEVSLNDLNKPSVALTNQVM
TADWRSRNAFPRGFANKAEMLQVEAKVRALLQL

Nucleotide

• Length: 342 bp

>T71729 NZ_CP019092:1757552-1757893 [Xanthomonas oryzae pv. oryzae]
ATGGTAAATCCCGGGTGGGTTCCGCGCAGGTCAGAAATTATTCATTTGGATGATGTGGGTGGGGCCGGTCATGAGCAGCG
TGGGGACCGGCCACACTTGGTTCTCAGTTCGCAAGGCTACAACGACACAACTAGTCTAGTGGTTTGCGTTCCTGTCACAA
CTAAACCCAAAGGCAATCCTTTTGAAGTAAGCCTTAATGATTTGAACAAGCCAAGTGTTGCTTTAACAAATCAGGTCATG
ACGGCAGATTGGCGCAGTAGAAATGCTTTTCCCCGAGGGTTTGCTAATAAAGCTGAAATGCTCCAAGTTGAAGCCAAGGT
TCGCGCTTTGCTTCAACTTTGA

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 8786.89 Da
• Isoelectric Point: 4.3753

>AT71729 WP_017154976.1 NZ_CP019092:1757316-1757558 [Xanthomonas oryzae pv. oryzae]
MAVLKMWGNSAAVRIPATYLEESKFSIDEPLVITAEEGRIVIESSKPSYNLADLVAQITPENTHGFAGHSQRVGAEDIEW

Nucleotide

• Length: 243 bp

>AT71729 NZ_CP019092:1757316-1757558 [Xanthomonas oryzae pv. oryzae]
ATGGCTGTTTTGAAGATGTGGGGGAATAGTGCTGCAGTTCGAATCCCGGCGACCTATCTCGAGGAGTCCAAGTTTTCTAT
TGACGAGCCTCTTGTAATCACTGCGGAGGAAGGTCGCATTGTGATCGAGTCGAGTAAGCCGTCTTATAACCTCGCGGACT
TGGTTGCTCAAATCACTCCAGAAAACACGCACGGCTTTGCTGGGCATTCCCAGAGAGTCGGGGCGGAGGATATTGAATGG
TAA

Structures

Antitoxin

• AlphaFold DB: A0A411Y3T7