Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 4280962..4281323 Replicon chromosome
Accession NZ_CP019091
Organism Xanthomonas oryzae pv. oryzae strain MAI134

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag BVV20_RS20620 Protein ID WP_011257368.1
Coordinates 4280962..4281096 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag BVV20_RS20625 Protein ID WP_011407410.1
Coordinates 4281171..4281323 (-) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BVV20_RS20605 4277979..4279001 - 1023 WP_199435630.1 MBL fold metallo-hydrolase -
BVV20_RS20610 4279054..4280343 - 1290 WP_101838712.1 tryptophan--tRNA ligase -
BVV20_RS20615 4280512..4280721 - 210 WP_101838994.1 CsbD family protein -
BVV20_RS20620 4280962..4281096 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
BVV20_RS20625 4281171..4281323 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
BVV20_RS20630 4281431..4282354 - 924 WP_053512953.1 arginase -
BVV20_RS20635 4282676..4283341 + 666 WP_101838713.1 hypothetical protein -
BVV20_RS20640 4283338..4283880 + 543 WP_101838714.1 GTPase -
BVV20_RS20650 4284372..4285055 + 684 WP_024744474.1 dTMP kinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T71728 WP_011257368.1 NZ_CP019091:c4281096-4280962 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T71728 NZ_CP019091:c4281096-4280962 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT71728 WP_011407410.1 NZ_CP019091:c4281323-4281171 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT71728 NZ_CP019091:c4281323-4281171 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40


Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References