Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4227993..4228354 Replicon chromosome
Accession NZ_CP019088
Organism Xanthomonas oryzae pv. oryzae strain MAI99

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag BVV10_RS20225 Protein ID WP_011257368.1
Coordinates 4227993..4228127 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag BVV10_RS20230 Protein ID WP_011407410.1
Coordinates 4228202..4228354 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BVV10_RS20210 4225010..4226032 - 1023 WP_165403720.1 MBL fold metallo-hydrolase -
BVV10_RS20215 4226085..4227374 - 1290 WP_024744479.1 tryptophan--tRNA ligase -
BVV10_RS20220 4227543..4227752 - 210 WP_024744478.1 CsbD family protein -
BVV10_RS20225 4227993..4228127 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
BVV10_RS20230 4228202..4228354 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
BVV10_RS20235 4228462..4229385 - 924 WP_053512953.1 arginase -
BVV10_RS20240 4229707..4230372 + 666 WP_024744476.1 hypothetical protein -
BVV10_RS20245 4230369..4230911 + 543 WP_024744475.1 GTPase -
BVV10_RS20255 4231415..4232098 + 684 WP_024744474.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T71723 WP_011257368.1 NZ_CP019088:c4228127-4227993 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T71723 NZ_CP019088:c4228127-4227993 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT71723 WP_011407410.1 NZ_CP019088:c4228354-4228202 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT71723 NZ_CP019088:c4228354-4228202 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References