71721

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4234214..4234575 Replicon chromosome
Accession NZ_CP019087
Organism Xanthomonas oryzae pv. oryzae strain MAI95

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag BVV18_RS20245 Protein ID WP_011257368.1
Coordinates 4234214..4234348 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag BVV18_RS20250 Protein ID WP_011407410.1
Coordinates 4234423..4234575 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BVV18_RS20230 4231231..4232253 - 1023 WP_165403720.1 MBL fold metallo-hydrolase -
BVV18_RS20235 4232306..4233595 - 1290 WP_024744479.1 tryptophan--tRNA ligase -
BVV18_RS20240 4233764..4233973 - 210 WP_024744478.1 CsbD family protein -
BVV18_RS20245 4234214..4234348 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
BVV18_RS20250 4234423..4234575 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
BVV18_RS20255 4234683..4235606 - 924 WP_053512953.1 arginase -
BVV18_RS20260 4235928..4236593 + 666 WP_024744476.1 hypothetical protein -
BVV18_RS20265 4236590..4237132 + 543 WP_024744475.1 GTPase -
BVV18_RS20275 4237636..4238319 + 684 WP_024744474.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T71721 WP_011257368.1 NZ_CP019087:c4234348-4234214 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T71721 NZ_CP019087:c4234348-4234214 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT71721 WP_011407410.1 NZ_CP019087:c4234575-4234423 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT71721 NZ_CP019087:c4234575-4234423 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References