Detailed information of TA system TA071716

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mazEF/PRK09907-MazE
• Location: 1757317..1757894
• Replicon: chromosome
• Accession: NZ_CP019085
• Organism: Xanthomonas oryzae pv. oryzae strain MAI68

Toxin (Protein)

• Gene name: mazF
• Uniprot ID: -
• Locus tag: BVV16_RS08805
• Protein ID: WP_196381723.1
• Coordinates: 1757598..1757894 (+)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: mazE
• Uniprot ID: A0A411Y3T7
• Locus tag: BVV16_RS08800
• Protein ID: WP_017154976.1
• Coordinates: 1757317..1757559 (+)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BVV16_RS08780	1753479..1754063	-	585	WP_024743447.1	NAD(P)H-dependent oxidoreductase	-
BVV16_RS08785	1754163..1755179	+	1017	WP_024743446.1	LysR family transcriptional regulator	-
BVV16_RS08795	1755731..1757221	+	1491	WP_033003336.1	site-specific integrase	-
BVV16_RS08800	1757317..1757559	+	243	WP_017154976.1	hypothetical protein	Antitoxin
BVV16_RS08805	1757598..1757894	+	297	WP_196381723.1	type II toxin-antitoxin system PemK/MazF family toxin	Toxin
BVV16_RS08810	1758016..1758381	+	366	Protein_1600	transposase	-
BVV16_RS08815	1758447..1759548	+	1102	WP_107490965.1	IS3 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (6-95)

Antitoxin

• Antitoxin PemI-like (4-76)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 10706.15 Da
• Isoelectric Point: 8.0458

>T71716 WP_196381723.1 NZ_CP019085:1757598-1757894 [Xanthomonas oryzae pv. oryzae]
MDDVGGAGHEQRGDRPHLVLSSQGYNDTTSLVVCVPVTTKPKGNPFEVSLNDLNKPSVALTNQVMTADWRSRNAFPRGFA
NKAEMLQVEAKVRALLQL

Nucleotide

• Length: 297 bp

>T71716 NZ_CP019085:1757598-1757894 [Xanthomonas oryzae pv. oryzae]
TTGGATGATGTGGGTGGGGCCGGTCATGAGCAGCGTGGGGACCGGCCACACTTGGTTCTCAGTTCGCAAGGCTACAACGA
CACAACTAGTCTAGTGGTTTGCGTTCCTGTCACAACTAAACCCAAAGGCAATCCTTTTGAAGTAAGCCTTAATGATTTGA
ACAAGCCAAGTGTTGCTTTAACAAATCAGGTCATGACGGCAGATTGGCGCAGTAGAAATGCTTTTCCCCGAGGGTTTGCT
AATAAAGCTGAAATGCTCCAAGTTGAAGCCAAGGTTCGCGCTTTGCTTCAACTTTGA

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 8786.89 Da
• Isoelectric Point: 4.3753

>AT71716 WP_017154976.1 NZ_CP019085:1757317-1757559 [Xanthomonas oryzae pv. oryzae]
MAVLKMWGNSAAVRIPATYLEESKFSIDEPLVITAEEGRIVIESSKPSYNLADLVAQITPENTHGFAGHSQRVGAEDIEW

Nucleotide

• Length: 243 bp

>AT71716 NZ_CP019085:1757317-1757559 [Xanthomonas oryzae pv. oryzae]
ATGGCTGTTTTGAAGATGTGGGGGAATAGTGCTGCAGTTCGAATCCCGGCGACCTATCTCGAGGAGTCCAAGTTTTCTAT
TGACGAGCCTCTTGTAATCACTGCGGAGGAAGGTCGCATTGTGATCGAGTCGAGTAAGCCGTCTTATAACCTCGCGGACT
TGGTTGCTCAAATCACTCCAGAAAACACGCACGGCTTTGCTGGGCATTCCCAGAGAGTCGGGGCGGAGGATATTGAATGG
TAA

Structures

Antitoxin

• AlphaFold DB: A0A411Y3T7