Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 6101474..6102132 Replicon chromosome
Accession NZ_CP019082
Organism Paludisphaera borealis strain PX4

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BSF38_RS23630 Protein ID WP_168189439.1
Coordinates 6101716..6102132 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BSF38_RS23625 Protein ID WP_076349562.1
Coordinates 6101474..6101713 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSF38_RS23610 6097008..6098540 + 1533 WP_076349559.1 hypothetical protein -
BSF38_RS23615 6099089..6099856 - 768 WP_076349560.1 glucose 1-dehydrogenase -
BSF38_RS23620 6100305..6101420 + 1116 WP_076349561.1 aminopeptidase -
BSF38_RS23625 6101474..6101713 + 240 WP_076349562.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
BSF38_RS23630 6101716..6102132 + 417 WP_168189439.1 type II toxin-antitoxin system VapC family toxin Toxin
BSF38_RS23635 6102253..6102663 + 411 WP_076349564.1 hypothetical protein -
BSF38_RS23640 6103013..6104140 + 1128 WP_083713346.1 DNA polymerase IV -
BSF38_RS23645 6104320..6104616 - 297 WP_076349565.1 hypothetical protein -
BSF38_RS23650 6104691..6106619 - 1929 WP_076349566.1 dihydroxy-acid dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-60)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14729.16 Da        Isoelectric Point: 7.2794

>T71715 WP_168189439.1 NZ_CP019082:6101716-6102132 [Paludisphaera borealis]
VLLDTCVLAEIRLPEGDPLVKSAVREIPADDLYLSVLSVGEIAKGIALLAVGRKKKALSSWLVALETQFGDRILGVDVET
ARIWGELTARSQKTGVVIPASDGLLAATALRHGLHVMTRNTRHFEASGALLINPWPGA

Download         Length: 417 bp

>T71715 NZ_CP019082:6101716-6102132 [Paludisphaera borealis]
GTGCTGCTTGACACCTGCGTCCTCGCGGAGATTCGGCTGCCCGAGGGCGATCCCTTGGTGAAGTCGGCGGTACGGGAGAT
TCCCGCGGACGACCTTTACCTTAGCGTGCTGTCCGTTGGCGAGATCGCCAAAGGCATCGCCCTGCTGGCCGTCGGCCGGA
AGAAGAAAGCCCTCTCCTCGTGGCTTGTGGCGCTCGAAACGCAGTTCGGCGACCGCATCCTCGGCGTCGACGTCGAGACG
GCCAGGATCTGGGGCGAATTGACGGCGCGATCGCAAAAGACCGGCGTCGTCATCCCCGCCTCCGACGGCCTCCTCGCCGC
AACCGCCCTCCGTCATGGGCTCCACGTCATGACCCGAAATACGCGTCACTTCGAGGCAAGCGGGGCGCTTCTCATCAACC
CTTGGCCGGGCGCGTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8974.18 Da        Isoelectric Point: 4.7719

>AT71715 WP_076349562.1 NZ_CP019082:6101474-6101713 [Paludisphaera borealis]
MTWKLAEAKNRLTEVVNLALTEGPQTITRRSDTVVVISAARYAELTGRKPDFKDFLFQGESFEGLDLTRDQSPMRDVEL

Download         Length: 240 bp

>AT71715 NZ_CP019082:6101474-6101713 [Paludisphaera borealis]
ATGACCTGGAAACTTGCCGAAGCCAAAAACCGACTCACCGAAGTTGTGAACCTGGCGCTCACCGAGGGGCCGCAGACGAT
CACCAGGCGGAGTGATACGGTCGTCGTCATTTCGGCGGCGAGGTATGCCGAATTGACGGGTCGGAAGCCCGATTTCAAGG
ACTTTCTCTTCCAGGGGGAATCGTTCGAGGGGCTCGACCTGACGCGTGATCAGAGCCCGATGCGGGACGTCGAGTTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References