Detailed information of TA system TA071674

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): prpT-prpA/ParE-CC2985
• Location: 31146..31692
• Replicon: plasmid unnamed2
• Accession: NZ_CP019064
• Organism: Rahnella sp. ERMR1:05

Toxin (Protein)

• Gene name: PrpT
• Uniprot ID: -
• Locus tag: BV494_RS24070
• Protein ID: WP_104925332.1
• Coordinates: 31396..31692 (+)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: PrpA
• Uniprot ID: -
• Locus tag: BV494_RS24065
• Protein ID: WP_104925331.1
• Coordinates: 31146..31409 (+)
• Length: 88 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BV494_RS24045	26521..26817	-	297	Protein_30	transposase	-
BV494_RS24050	26865..28634	-	1770	WP_104925328.1	EAL domain-containing protein	-
BV494_RS24065	31146..31409	+	264	WP_104925331.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
BV494_RS24070	31396..31692	+	297	WP_104925332.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BV494_RS24080	32668..33924	-	1257	WP_104925473.1	dicarboxylate/amino acid:cation symporter	-
BV494_RS24085	34454..35353	-	900	WP_104925334.1	GGDEF domain-containing protein	-
BV494_RS24090	35568..36359	-	792	WP_104925335.1	spermidine synthase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Conjugative plasmid	-	-	1..229977	229977

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-90)

Antitoxin

• Antitoxin ParD (1-77)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 11382.94 Da
• Isoelectric Point: 4.6485

>T71674 WP_104925332.1 NZ_CP019064:31396-31692 [Rahnella sp. ERMR1:05]
MKEINLTPKANEDLEDIWSYSQENFGVVKADDYISRFSDIFDVLATHEIGSLRPELGEHIFSLPIEKHVIFFIPSDTAIT
VIRILNQSQDVLRHLVWR

Nucleotide

• Length: 297 bp

>T71674 NZ_CP019064:31396-31692 [Rahnella sp. ERMR1:05]
ATGAAAGAAATTAACCTGACGCCTAAAGCAAACGAAGATTTGGAAGATATCTGGTCGTATAGTCAGGAAAATTTTGGCGT
CGTTAAAGCAGACGATTATATCAGCCGTTTTTCCGACATATTTGATGTGCTAGCAACCCATGAGATCGGTTCTCTAAGAC
CAGAATTAGGCGAACACATTTTTTCCTTACCGATTGAGAAACATGTGATTTTCTTCATTCCCTCCGATACTGCTATCACA
GTGATCCGTATTCTTAATCAGTCACAGGACGTTCTTCGCCATTTGGTCTGGCGTTAA

Antitoxin

Protein

• Length: 88 a.a.
• Molecular weight: 10056.33 Da
• Isoelectric Point: 6.4730

>AT71674 WP_104925331.1 NZ_CP019064:31146-31409 [Rahnella sp. ERMR1:05]
MARTMTVDLGEELREFIDSLVQSGDYRTQSEVLRDALRLLREKQAESHLQTLRDLLAEGVSSGTPETWDKNSFLQRVKGK
VRLHERN

Nucleotide

• Length: 264 bp

>AT71674 NZ_CP019064:31146-31409 [Rahnella sp. ERMR1:05]
ATGGCTAGAACTATGACAGTTGACCTTGGTGAAGAACTACGGGAATTCATCGATTCTCTTGTTCAATCCGGGGATTACAG
AACGCAAAGTGAAGTACTTCGCGATGCACTGCGCCTGTTACGTGAAAAACAGGCGGAATCCCACCTGCAAACTTTGCGCG
ATTTATTGGCTGAGGGCGTTAGCAGCGGAACGCCAGAGACATGGGATAAGAACTCATTCCTGCAGCGAGTAAAAGGAAAG
GTCCGACTGCATGAAAGAAATTAA