Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataT-KacA/DUF1778(antitoxin)
Location 511642..512439 Replicon plasmid unnamed1
Accession NZ_CP019063
Organism Rahnella sp. ERMR1:05

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag BV494_RS23705 Protein ID WP_104925230.1
Coordinates 511642..512166 (-) Length 175 a.a.

Antitoxin (Protein)


Gene name KacA Uniprot ID -
Locus tag BV494_RS23710 Protein ID WP_104925306.1
Coordinates 512170..512439 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BV494_RS23685 509109..509227 + 119 Protein_431 MFS transporter -
BV494_RS23690 509923..510735 + 813 WP_104925227.1 methionine ABC transporter substrate-binding lipoprotein MetQ -
BV494_RS23695 510821..511000 - 180 WP_104925228.1 DUF2158 domain-containing protein -
BV494_RS23700 511146..511577 + 432 WP_104925229.1 OsmC family protein -
BV494_RS23705 511642..512166 - 525 WP_104925230.1 GNAT family N-acetyltransferase Toxin
BV494_RS23710 512170..512439 - 270 WP_104925306.1 DUF1778 domain-containing protein Antitoxin
BV494_RS23715 512830..513738 + 909 WP_104925231.1 LysR family transcriptional regulator -
BV494_RS23720 513885..515348 + 1464 WP_104925232.1 gamma-aminobutyraldehyde dehydrogenase -
BV494_RS23725 515383..516522 + 1140 WP_104925233.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - clpV/tssH / hcp/tssD / vipB/tssC / vipA/tssB / mgtB 1..549463 549463


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(86-149)

Antitoxin

Vibrio phage ICP1, Orf50

(2-88)


Sequences

Toxin        


Download         Length: 175 a.a.        Molecular weight: 19607.28 Da        Isoelectric Point: 6.8402

>T71672 WP_104925230.1 NZ_CP019063:c512166-511642 [Rahnella sp. ERMR1:05]
VADLTIGIFSKDDEYDLSDFDCGEESLNNFLTAHLARQHKNRILRAYLLTTKEPKQRVLGYYTLSGSCFEKETLPTNSQK
RKVPYENVPSITLGRLAVHKDLQGQEWGTTLVTHAMGVVFHASKAVGVHAMFVDALNERAKQFYLKLDFISLTGDNANSL
FLPTKSIEELFAHQ

Download         Length: 525 bp

>T71672 NZ_CP019063:c512166-511642 [Rahnella sp. ERMR1:05]
GTGGCTGATTTAACCATTGGAATTTTTTCTAAAGATGACGAATATGATTTATCAGATTTCGATTGTGGCGAAGAGTCTCT
GAATAATTTTCTTACCGCTCATCTGGCTCGTCAGCATAAGAACCGGATTTTACGCGCTTATCTGCTCACGACTAAAGAGC
CGAAACAAAGAGTACTCGGCTACTACACGTTATCCGGGAGCTGTTTTGAAAAGGAAACACTTCCCACGAATAGCCAGAAG
CGAAAAGTACCTTATGAAAACGTTCCAAGCATTACCTTAGGACGTTTAGCGGTTCATAAAGATTTACAGGGGCAGGAATG
GGGCACCACGCTTGTCACACATGCGATGGGCGTCGTCTTCCATGCTTCGAAGGCCGTCGGTGTCCATGCGATGTTTGTAG
ACGCGCTCAACGAGCGTGCGAAACAGTTCTATCTGAAACTGGATTTCATATCACTCACTGGTGATAACGCAAATTCGCTT
TTCCTGCCGACGAAGTCGATAGAAGAACTTTTTGCCCATCAGTAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10106.64 Da        Isoelectric Point: 10.3838

>AT71672 WP_104925306.1 NZ_CP019063:c512439-512170 [Rahnella sp. ERMR1:05]
MPAPKKQRIDLRLSDDDKSAIEEAAAISNQTITQFMVASASKRAAEVIEQHRRLILNNESWNLVMDAISHPPVLNDRLKR
AAKRLKNME

Download         Length: 270 bp

>AT71672 NZ_CP019063:c512439-512170 [Rahnella sp. ERMR1:05]
ATGCCAGCACCAAAGAAACAGCGCATCGATCTCAGGTTAAGTGACGACGACAAGAGCGCGATCGAAGAAGCGGCGGCAAT
ATCCAACCAGACAATTACCCAATTTATGGTTGCCAGTGCTTCTAAACGCGCTGCGGAAGTTATTGAACAGCACCGACGTC
TGATCCTTAACAACGAATCCTGGAATCTGGTGATGGATGCGATTAGTCACCCACCAGTGCTGAATGACAGGCTAAAACGA
GCGGCAAAACGTCTTAAAAACATGGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References