Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4488349..4489048 Replicon chromosome
Accession NZ_CP019062
Organism Rahnella sp. ERMR1:05

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag BV494_RS20790 Protein ID WP_104924539.1
Coordinates 4488596..4489048 (+) Length 151 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag BV494_RS20785 Protein ID WP_104924861.1
Coordinates 4488349..4488615 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BV494_RS20760 4484352..4484687 + 336 WP_104924534.1 DUF2002 family protein -
BV494_RS20765 4484742..4485182 - 441 WP_104924535.1 DUF1198 domain-containing protein -
BV494_RS20770 4485342..4486286 - 945 WP_104924536.1 6-phosphofructokinase II -
BV494_RS20775 4486472..4487002 + 531 WP_104924537.1 class IV adenylate cyclase -
BV494_RS20780 4487077..4488069 - 993 WP_104924538.1 tRNA-modifying protein YgfZ -
BV494_RS20785 4488349..4488615 + 267 WP_104924861.1 FAD assembly factor SdhE Antitoxin
BV494_RS20790 4488596..4489048 + 453 WP_104924539.1 protein YgfX Toxin
BV494_RS20795 4489076..4489594 - 519 WP_104924540.1 flavodoxin FldB -
BV494_RS20800 4489705..4490664 + 960 WP_104924541.1 site-specific tyrosine recombinase XerD -
BV494_RS20805 4490690..4491409 + 720 WP_104924542.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
BV494_RS20810 4491416..4493149 + 1734 WP_104924543.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-140)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 151 a.a.        Molecular weight: 17482.65 Da        Isoelectric Point: 11.6634

>T71670 WP_104924539.1 NZ_CP019062:4488596-4489048 [Rahnella sp. ERMR1:05]
VALWRCDLRVSWRSQLISLGSYGGVMLLILLAPWPAGYWPVWMTLLLLVLFECIRSQRRITARTGEIILLEDNRLLWRGH
EWQIKQPVWMISSGVLLTLRREKRKGGLAQAMRSSRQRLWLASDSMGLDEWRHLRQILLRGDPRSPAEPG

Download         Length: 453 bp

>T71670 NZ_CP019062:4488596-4489048 [Rahnella sp. ERMR1:05]
GTGGCCCTGTGGCGATGTGATCTCAGGGTGTCCTGGCGCAGTCAGCTCATTTCACTGGGGTCTTACGGTGGCGTGATGTT
ACTGATTTTGCTGGCACCCTGGCCTGCAGGCTACTGGCCGGTATGGATGACACTGCTTTTGCTGGTGCTGTTCGAATGCA
TCCGCAGCCAGCGGCGTATTACGGCCCGAACCGGCGAAATCATCCTGCTTGAGGATAACCGCCTGCTGTGGCGTGGTCAT
GAATGGCAGATTAAGCAACCGGTCTGGATGATAAGCAGCGGCGTGTTGCTGACGTTGCGTCGTGAAAAACGCAAAGGCGG
GTTGGCGCAGGCGATGCGCAGCTCAAGACAGCGGTTATGGCTGGCGTCGGACAGTATGGGGCTGGATGAATGGCGGCATT
TGCGCCAGATATTGTTGCGTGGTGATCCCCGCAGCCCGGCTGAACCGGGCTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10392.85 Da        Isoelectric Point: 5.6134

>AT71670 WP_104924861.1 NZ_CP019062:4488349-4488615 [Rahnella sp. ERMR1:05]
MDINNRSRIHWACRRGMRELDISIMPFFEHEYDSLTDADKELFARLLTSDDPDLFNWLMNHGEPKDTELQRMVALIQTRN
KARGPVAM

Download         Length: 267 bp

>AT71670 NZ_CP019062:4488349-4488615 [Rahnella sp. ERMR1:05]
CTGGATATCAATAACCGTTCCCGTATTCACTGGGCCTGTCGTCGCGGTATGCGCGAGCTGGATATCTCCATCATGCCGTT
TTTTGAACATGAATATGATTCGCTGACCGATGCCGACAAAGAGCTGTTTGCGCGTCTGCTGACCTCTGACGATCCGGATT
TGTTCAACTGGCTGATGAACCACGGCGAACCGAAAGACACCGAATTACAGCGTATGGTCGCCCTTATTCAGACTCGAAAC
AAAGCCCGTGGCCCTGTGGCGATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References