Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | pmenTA/darT(toxin) |
Location | 4247874..4249594 | Replicon | chromosome |
Accession | NZ_CP019062 | ||
Organism | Rahnella sp. ERMR1:05 |
Toxin (Protein)
Gene name | pmenT | Uniprot ID | - |
Locus tag | BV494_RS19630 | Protein ID | WP_104924349.1 |
Coordinates | 4247874..4248530 (+) | Length | 219 a.a. |
Antitoxin (Protein)
Gene name | pmenA | Uniprot ID | - |
Locus tag | BV494_RS19635 | Protein ID | WP_104924350.1 |
Coordinates | 4248527..4249594 (+) | Length | 356 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BV494_RS19615 | 4243879..4244118 | + | 240 | WP_104924346.1 | transcription factor | - |
BV494_RS19620 | 4244158..4246605 | + | 2448 | WP_104924347.1 | type I restriction-modification system subunit M | - |
BV494_RS19625 | 4246605..4247861 | + | 1257 | WP_104924348.1 | restriction endonuclease subunit S | - |
BV494_RS19630 | 4247874..4248530 | + | 657 | WP_104924349.1 | DUF4433 domain-containing protein | Toxin |
BV494_RS19635 | 4248527..4249594 | + | 1068 | WP_104924350.1 | macro domain-containing protein | Antitoxin |
BV494_RS19640 | 4249615..4252710 | + | 3096 | WP_104924351.1 | HsdR family type I site-specific deoxyribonuclease | - |
BV494_RS19645 | 4252710..4253426 | + | 717 | WP_104924352.1 | M48 family metallopeptidase | - |
BV494_RS19655 | 4253897..4254064 | - | 168 | WP_104924852.1 | AlpA family phage regulatory protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 219 a.a. Molecular weight: 25257.79 Da Isoelectric Point: 7.5072
>T71668 WP_104924349.1 NZ_CP019062:4247874-4248530 [Rahnella sp. ERMR1:05]
MAYDYSANLNPEKALIWRIVHRDNIPWILDNGLHCGNSPVQAENWINIGNPELIDKRAGHLVPTGTGGTLHDYVPFYFTP
FSPMLMNIRSGRGGIKQRPNEEIVILVSSLRHLAAQKVPFVFTDSHAYYNLANYYTDLNNLHRIDWPILQARDFRRDQDD
LGKFERYQAEALIWKHCPITLLGGMICYNDGVRLQLEQWMSQRNLSMPVHTRAGWYFS
MAYDYSANLNPEKALIWRIVHRDNIPWILDNGLHCGNSPVQAENWINIGNPELIDKRAGHLVPTGTGGTLHDYVPFYFTP
FSPMLMNIRSGRGGIKQRPNEEIVILVSSLRHLAAQKVPFVFTDSHAYYNLANYYTDLNNLHRIDWPILQARDFRRDQDD
LGKFERYQAEALIWKHCPITLLGGMICYNDGVRLQLEQWMSQRNLSMPVHTRAGWYFS
Download Length: 657 bp
>T71668 NZ_CP019062:4247874-4248530 [Rahnella sp. ERMR1:05]
ATGGCTTATGACTACAGCGCTAATCTCAACCCCGAAAAAGCCCTGATCTGGCGCATTGTCCATCGGGACAATATCCCGTG
GATCCTGGACAACGGTCTGCACTGTGGCAACAGTCCGGTGCAGGCGGAAAACTGGATTAATATCGGTAACCCGGAGCTTA
TCGACAAACGTGCCGGACATCTGGTACCTACCGGAACGGGAGGGACGCTGCATGACTATGTGCCGTTTTACTTTACTCCT
TTCTCGCCAATGCTGATGAATATTCGCAGCGGGCGTGGCGGCATTAAGCAGCGCCCCAATGAGGAAATCGTCATTCTGGT
CAGCAGCCTGCGACACTTGGCGGCGCAGAAGGTCCCCTTCGTCTTTACCGACAGCCACGCCTACTATAATCTGGCAAATT
ACTATACCGATCTAAACAATCTGCATCGGATCGACTGGCCCATCTTACAAGCGCGGGATTTCCGTCGCGATCAGGACGAT
CTTGGCAAGTTTGAACGCTATCAGGCTGAGGCGTTAATCTGGAAGCACTGCCCAATCACACTGCTGGGCGGGATGATTTG
TTACAACGATGGCGTCAGGTTACAATTAGAGCAGTGGATGTCACAACGCAATCTGTCAATGCCCGTTCACACACGGGCCG
GGTGGTACTTCTCATGA
ATGGCTTATGACTACAGCGCTAATCTCAACCCCGAAAAAGCCCTGATCTGGCGCATTGTCCATCGGGACAATATCCCGTG
GATCCTGGACAACGGTCTGCACTGTGGCAACAGTCCGGTGCAGGCGGAAAACTGGATTAATATCGGTAACCCGGAGCTTA
TCGACAAACGTGCCGGACATCTGGTACCTACCGGAACGGGAGGGACGCTGCATGACTATGTGCCGTTTTACTTTACTCCT
TTCTCGCCAATGCTGATGAATATTCGCAGCGGGCGTGGCGGCATTAAGCAGCGCCCCAATGAGGAAATCGTCATTCTGGT
CAGCAGCCTGCGACACTTGGCGGCGCAGAAGGTCCCCTTCGTCTTTACCGACAGCCACGCCTACTATAATCTGGCAAATT
ACTATACCGATCTAAACAATCTGCATCGGATCGACTGGCCCATCTTACAAGCGCGGGATTTCCGTCGCGATCAGGACGAT
CTTGGCAAGTTTGAACGCTATCAGGCTGAGGCGTTAATCTGGAAGCACTGCCCAATCACACTGCTGGGCGGGATGATTTG
TTACAACGATGGCGTCAGGTTACAATTAGAGCAGTGGATGTCACAACGCAATCTGTCAATGCCCGTTCACACACGGGCCG
GGTGGTACTTCTCATGA
Antitoxin
Download Length: 356 a.a. Molecular weight: 40767.04 Da Isoelectric Point: 5.9022
>AT71668 WP_104924350.1 NZ_CP019062:4248527-4249594 [Rahnella sp. ERMR1:05]
MIAYTQGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPDNMKAYALACKQKQVMTGKMFITETGELMGPRWIVNFPTK
QHWRADSRMEWIEDGLQDLRRFLSEEKVQSIAIPPLGAGNGGLNWPDVRARIESALGDLRDIEILIYEPTEKYQNVAKST
GVKKLTPARAMIAELVRRYWVLGMECSLLEIQKLAWLLQRAIELHQQEDVLKLRFEAHNYGPFSPNLNHLLNALDGTYLK
AEKRIPDSQPLDVIWFNDREKEHVNLWLNNEAKEWLPALEQVSQLIDGFESPFGLELLATVDWLLTRGECLPTLDSVKEG
LHQWPAGERWASRKMKLFDDNHLQFAINRVMEFHC
MIAYTQGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPDNMKAYALACKQKQVMTGKMFITETGELMGPRWIVNFPTK
QHWRADSRMEWIEDGLQDLRRFLSEEKVQSIAIPPLGAGNGGLNWPDVRARIESALGDLRDIEILIYEPTEKYQNVAKST
GVKKLTPARAMIAELVRRYWVLGMECSLLEIQKLAWLLQRAIELHQQEDVLKLRFEAHNYGPFSPNLNHLLNALDGTYLK
AEKRIPDSQPLDVIWFNDREKEHVNLWLNNEAKEWLPALEQVSQLIDGFESPFGLELLATVDWLLTRGECLPTLDSVKEG
LHQWPAGERWASRKMKLFDDNHLQFAINRVMEFHC
Download Length: 1068 bp
>AT71668 NZ_CP019062:4248527-4249594 [Rahnella sp. ERMR1:05]
ATGATCGCATATACACAAGGCAATTTACTGGACGCGCCCGTGGAAGCACTGGTGAATACGGTTAATACCGTCGGCGTCAT
GGGTAAAGGCATCGCGCTAATGTTCAAAGAGCGCTTCCCCGATAATATGAAAGCCTATGCTCTCGCCTGCAAACAAAAGC
AGGTCATGACCGGCAAGATGTTTATTACCGAAACCGGCGAGCTGATGGGGCCGCGCTGGATCGTCAACTTCCCAACCAAG
CAGCACTGGCGCGCCGACTCCCGCATGGAGTGGATTGAAGACGGCTTGCAGGACCTACGCCGCTTTTTGAGCGAAGAGAA
AGTGCAGTCCATCGCCATTCCTCCACTGGGCGCAGGCAACGGTGGCCTGAACTGGCCGGACGTCCGGGCGCGGATTGAAT
CTGCGCTGGGCGACCTTCGGGACATAGAAATCCTGATTTATGAGCCTACCGAAAAATACCAGAACGTCGCCAAGAGCACC
GGCGTAAAAAAGCTCACACCCGCCAGAGCGATGATCGCTGAACTAGTGCGCCGCTACTGGGTGCTGGGCATGGAGTGCAG
TTTGCTGGAAATCCAGAAGCTGGCATGGCTGTTACAACGCGCTATTGAACTGCACCAGCAGGAGGACGTGCTTAAGCTGC
GCTTTGAGGCGCACAATTACGGTCCCTTCTCCCCCAACCTGAACCATCTGCTTAACGCGCTGGACGGCACCTATCTGAAA
GCCGAGAAACGCATCCCGGACAGCCAGCCGCTGGACGTGATCTGGTTTAACGATCGGGAAAAAGAACACGTCAACCTCTG
GCTGAACAACGAGGCCAAAGAGTGGCTACCGGCGCTTGAGCAGGTCAGCCAGTTGATTGACGGCTTTGAATCGCCGTTTG
GTCTGGAGCTGCTGGCGACCGTTGACTGGCTGCTGACCCGAGGAGAATGCCTGCCCACGCTGGATTCCGTGAAAGAGGGG
CTGCACCAATGGCCTGCGGGTGAACGCTGGGCCAGCCGTAAGATGAAGCTGTTTGATGATAATCATCTTCAATTCGCCAT
AAACCGCGTGATGGAGTTCCATTGCTGA
ATGATCGCATATACACAAGGCAATTTACTGGACGCGCCCGTGGAAGCACTGGTGAATACGGTTAATACCGTCGGCGTCAT
GGGTAAAGGCATCGCGCTAATGTTCAAAGAGCGCTTCCCCGATAATATGAAAGCCTATGCTCTCGCCTGCAAACAAAAGC
AGGTCATGACCGGCAAGATGTTTATTACCGAAACCGGCGAGCTGATGGGGCCGCGCTGGATCGTCAACTTCCCAACCAAG
CAGCACTGGCGCGCCGACTCCCGCATGGAGTGGATTGAAGACGGCTTGCAGGACCTACGCCGCTTTTTGAGCGAAGAGAA
AGTGCAGTCCATCGCCATTCCTCCACTGGGCGCAGGCAACGGTGGCCTGAACTGGCCGGACGTCCGGGCGCGGATTGAAT
CTGCGCTGGGCGACCTTCGGGACATAGAAATCCTGATTTATGAGCCTACCGAAAAATACCAGAACGTCGCCAAGAGCACC
GGCGTAAAAAAGCTCACACCCGCCAGAGCGATGATCGCTGAACTAGTGCGCCGCTACTGGGTGCTGGGCATGGAGTGCAG
TTTGCTGGAAATCCAGAAGCTGGCATGGCTGTTACAACGCGCTATTGAACTGCACCAGCAGGAGGACGTGCTTAAGCTGC
GCTTTGAGGCGCACAATTACGGTCCCTTCTCCCCCAACCTGAACCATCTGCTTAACGCGCTGGACGGCACCTATCTGAAA
GCCGAGAAACGCATCCCGGACAGCCAGCCGCTGGACGTGATCTGGTTTAACGATCGGGAAAAAGAACACGTCAACCTCTG
GCTGAACAACGAGGCCAAAGAGTGGCTACCGGCGCTTGAGCAGGTCAGCCAGTTGATTGACGGCTTTGAATCGCCGTTTG
GTCTGGAGCTGCTGGCGACCGTTGACTGGCTGCTGACCCGAGGAGAATGCCTGCCCACGCTGGATTCCGTGAAAGAGGGG
CTGCACCAATGGCCTGCGGGTGAACGCTGGGCCAGCCGTAAGATGAAGCTGTTTGATGATAATCATCTTCAATTCGCCAT
AAACCGCGTGATGGAGTTCCATTGCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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