Detailed information of TA system TA071666

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tad-ata/COG5606-COG4679
• Location: 3401984..3402654
• Replicon: chromosome
• Accession: NZ_CP019062
• Organism: Rahnella sp. ERMR1:05

Toxin (Protein)

• Gene name: tad
• Uniprot ID: -
• Locus tag: BV494_RS15755
• Protein ID: WP_101077525.1
• Coordinates: 3401984..3402331 (+)
• Length: 116 a.a.

Antitoxin (Protein)

• Gene name: ata
• Uniprot ID: -
• Locus tag: BV494_RS15760
• Protein ID: WP_104923700.1
• Coordinates: 3402331..3402654 (+)
• Length: 108 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BV494_RS15740	3397402..3399588	-	2187	WP_104923697.1	1,4-alpha-glucan branching protein GlgB	-
BV494_RS15745	3399996..3401099	-	1104	WP_104923698.1	aspartate-semialdehyde dehydrogenase	-
BV494_RS15750	3401317..3401910	+	594	WP_104923699.1	YhgN family NAAT transporter	-
BV494_RS15755	3401984..3402331	+	348	WP_101077525.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BV494_RS15760	3402331..3402654	+	324	WP_104923700.1	helix-turn-helix domain-containing protein	Antitoxin
BV494_RS15765	3402740..3404056	-	1317	WP_104923701.1	gluconate transporter	-
BV494_RS15770	3404304..3404819	+	516	WP_104923702.1	gluconokinase	-
BV494_RS15780	3404966..3405961	-	996	WP_104923704.1	gluconate operon transcriptional repressor GntR	-
BV494_RS15785	3406056..3406973	-	918	WP_104923705.1	LacI family transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-like (12-105)

Antitoxin

• HigA2-like, helix-turn-helix domain (14-92)

Sequences

Toxin

Protein

• Length: 116 a.a.
• Molecular weight: 12569.47 Da
• Isoelectric Point: 9.6269

>T71666 WP_101077525.1 NZ_CP019062:3401984-3402331 [Rahnella sp. ERMR1:05]
MKTLFWIGSSKKDLASLPEDIQDSFGYALHLAQTGSKHCHAKPLKGYKGAGVLEVVEDLSGDTYRAVYTVKIATAVYVLH
VFQKKSSSGIATPKPDIDKINERLKIAEAHARGQI

Nucleotide

• Length: 348 bp

>T71666 NZ_CP019062:3401984-3402331 [Rahnella sp. ERMR1:05]
ATGAAAACGCTTTTCTGGATTGGAAGCAGTAAAAAAGATTTGGCGTCATTGCCGGAAGATATTCAGGATTCTTTCGGTTA
CGCCCTGCATCTGGCGCAAACAGGCAGCAAACATTGTCATGCCAAGCCGTTGAAAGGCTACAAAGGTGCAGGCGTTTTGG
AAGTTGTGGAAGATCTGTCAGGTGATACTTATCGCGCGGTTTATACCGTGAAAATTGCCACCGCAGTGTATGTCTTACAC
GTTTTCCAGAAAAAGTCCTCAAGTGGTATCGCTACGCCAAAACCTGATATTGATAAGATCAACGAACGTCTGAAAATTGC
TGAAGCTCATGCAAGAGGACAAATTTAA

Antitoxin

Protein

• Length: 108 a.a.
• Molecular weight: 11691.71 Da
• Isoelectric Point: 9.0747

>AT71666 WP_104923700.1 NZ_CP019062:3402331-3402654 [Rahnella sp. ERMR1:05]
MKDPIEVEISSGNVYADIGLSDAEEMLIKAQLAQKIGELMQNRRLTQAAAAKLFGMTQPKVSALLRGQFRGISEAKMIEC
LNKLGRDVQIVIAESRQVTGTLKVVFA

Nucleotide

• Length: 324 bp

>AT71666 NZ_CP019062:3402331-3402654 [Rahnella sp. ERMR1:05]
ATGAAAGACCCCATTGAAGTTGAAATCAGCAGCGGGAATGTTTACGCCGACATCGGCTTATCCGATGCAGAAGAAATGCT
TATTAAAGCTCAGCTTGCTCAGAAAATCGGCGAGCTTATGCAGAACCGACGCCTGACTCAGGCTGCAGCCGCTAAGCTTT
TTGGCATGACTCAACCGAAAGTATCTGCACTCCTTCGTGGTCAGTTCCGTGGGATTAGCGAAGCGAAGATGATTGAGTGT
CTTAATAAGTTAGGCCGGGATGTGCAAATCGTTATCGCTGAGTCCCGGCAAGTCACTGGTACGTTGAAAGTCGTATTTGC
ATAA