Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/ParE-DnaT |
| Location | 57273..57795 | Replicon | plasmid p1540-1 |
| Accession | NZ_CP019052 | ||
| Organism | Escherichia coli strain CRE1540 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | U9YLU1 |
| Locus tag | BVL39_RS25890 | Protein ID | WP_000638823.1 |
| Coordinates | 57273..57554 (-) | Length | 94 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | U9Y7J1 |
| Locus tag | BVL39_RS25895 | Protein ID | WP_000121741.1 |
| Coordinates | 57544..57795 (-) | Length | 84 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BVL39_RS25855 | 53422..53742 | - | 321 | WP_000362080.1 | VirB3 family type IV secretion system protein | - |
| BVL39_RS25860 | 53813..54001 | - | 189 | WP_050567133.1 | hypothetical protein | - |
| BVL39_RS25865 | 54103..54687 | - | 585 | WP_001177113.1 | lytic transglycosylase domain-containing protein | - |
| BVL39_RS25870 | 54708..55106 | - | 399 | WP_072643816.1 | hypothetical protein | - |
| BVL39_RS25875 | 55225..55662 | - | 438 | WP_000539665.1 | type IV pilus biogenesis protein PilM | - |
| BVL39_RS25880 | 55668..56903 | - | 1236 | WP_015059538.1 | TcpQ domain-containing protein | - |
| BVL39_RS25885 | 56906..57205 | - | 300 | WP_000835764.1 | IncN plasmid KikA protein | - |
| BVL39_RS25890 | 57273..57554 | - | 282 | WP_000638823.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| BVL39_RS25895 | 57544..57795 | - | 252 | WP_000121741.1 | hypothetical protein | Antitoxin |
| BVL39_RS25900 | 57895..58530 | - | 636 | WP_015059536.1 | hypothetical protein | - |
| BVL39_RS25905 | 58603..58890 | - | 288 | WP_001032611.1 | EexN family lipoprotein | - |
| BVL39_RS25910 | 58903..59157 | - | 255 | WP_001043555.1 | EexN family lipoprotein | - |
| BVL39_RS25915 | 59159..59800 | - | 642 | WP_001425343.1 | conjugal transfer protein TrbJ | - |
| BVL39_RS25920 | 59806..60801 | - | 996 | WP_001028543.1 | type IV secretion system protein | - |
| BVL39_RS25925 | 60805..61062 | - | 258 | WP_000739144.1 | hypothetical protein | - |
| BVL39_RS25930 | 61059..61361 | - | 303 | WP_001360345.1 | hypothetical protein | - |
| BVL39_RS25935 | 61342..61599 | - | 258 | WP_001542015.1 | hypothetical protein | - |
| BVL39_RS25940 | 61632..62078 | - | 447 | WP_001243165.1 | hypothetical protein | - |
| BVL39_RS29290 | 62089..62259 | - | 171 | WP_000550720.1 | hypothetical protein | - |
| BVL39_RS25945 | 62263..62706 | - | 444 | WP_000964330.1 | NfeD family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Mobilizable plasmid | blaCTX-M-55 / mcr-1.1 | - | 1..65533 | 65533 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 94 a.a. Molecular weight: 10945.79 Da Isoelectric Point: 10.4997
>T71637 WP_000638823.1 NZ_CP019052:c57554-57273 [Escherichia coli]
MIYELAFDHRALKEWQKLGHTVREQFKKKLSERLINPRVPAAKLHGHTDRYKIKLRASGYRLVYQVIDEKVVLLVISVGK
REGSDVYHMADTR
MIYELAFDHRALKEWQKLGHTVREQFKKKLSERLINPRVPAAKLHGHTDRYKIKLRASGYRLVYQVIDEKVVLLVISVGK
REGSDVYHMADTR
Download Length: 282 bp
>T71637 NZ_CP019052:c57554-57273 [Escherichia coli]
ATGATTTATGAACTGGCATTTGACCACAGAGCACTGAAGGAATGGCAAAAACTCGGTCACACTGTTCGTGAGCAATTCAA
AAAGAAACTGTCAGAACGCCTGATAAATCCACGCGTCCCCGCAGCCAAGCTACATGGTCATACTGACCGTTACAAAATTA
AGCTTCGCGCATCCGGTTACAGGCTCGTTTATCAGGTAATTGATGAGAAGGTCGTTTTGCTTGTGATTTCTGTGGGAAAA
AGAGAAGGCAGCGACGTCTATCACATGGCAGATACCCGCTGA
ATGATTTATGAACTGGCATTTGACCACAGAGCACTGAAGGAATGGCAAAAACTCGGTCACACTGTTCGTGAGCAATTCAA
AAAGAAACTGTCAGAACGCCTGATAAATCCACGCGTCCCCGCAGCCAAGCTACATGGTCATACTGACCGTTACAAAATTA
AGCTTCGCGCATCCGGTTACAGGCTCGTTTATCAGGTAATTGATGAGAAGGTCGTTTTGCTTGTGATTTCTGTGGGAAAA
AGAGAAGGCAGCGACGTCTATCACATGGCAGATACCCGCTGA
Antitoxin
Download Length: 84 a.a. Molecular weight: 9223.38 Da Isoelectric Point: 3.9823
>AT71637 WP_000121741.1 NZ_CP019052:c57795-57544 [Escherichia coli]
MSYQILTTTAASITDLKKNPMGTVAEGEGDAVAILNRNEPAFYCVPPELYAYYRELAEDAELNAIADERMKNPDIVRVNL
DDL
MSYQILTTTAASITDLKKNPMGTVAEGEGDAVAILNRNEPAFYCVPPELYAYYRELAEDAELNAIADERMKNPDIVRVNL
DDL
Download Length: 252 bp
>AT71637 NZ_CP019052:c57795-57544 [Escherichia coli]
ATGAGCTACCAAATTCTGACTACGACAGCAGCCAGTATTACTGACCTGAAAAAAAATCCTATGGGAACTGTAGCCGAAGG
AGAAGGGGATGCCGTCGCAATCCTGAACCGAAATGAACCAGCGTTCTACTGTGTCCCACCAGAACTTTATGCCTACTACC
GGGAACTCGCTGAAGACGCTGAACTCAACGCAATTGCTGATGAAAGAATGAAAAATCCAGACATTGTAAGGGTTAACCTG
GATGATTTATGA
ATGAGCTACCAAATTCTGACTACGACAGCAGCCAGTATTACTGACCTGAAAAAAAATCCTATGGGAACTGTAGCCGAAGG
AGAAGGGGATGCCGTCGCAATCCTGAACCGAAATGAACCAGCGTTCTACTGTGTCCCACCAGAACTTTATGCCTACTACC
GGGAACTCGCTGAAGACGCTGAACTCAACGCAATTGCTGATGAAAGAATGAAAAATCCAGACATTGTAAGGGTTAACCTG
GATGATTTATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|