Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1962814..1962959 Replicon chromosome
Accession NZ_CP019047
Organism Klebsiella pneumoniae subsp. pneumoniae strain RJA166

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1962850..1962952 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1962814..1962959 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RJA_RS09710 1957944..1960004 + 2061 WP_004151449.1 oligopeptidase B -
RJA_RS09715 1960008..1960667 - 660 WP_002911407.1 exodeoxyribonuclease X -
RJA_RS09720 1960746..1960976 - 231 WP_002911406.1 DNA polymerase III subunit theta -
RJA_RS09725 1961089..1961463 + 375 WP_004151448.1 CopC domain-containing protein YobA -
RJA_RS09730 1961467..1962336 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
RJA_RS09735 1962353..1962691 + 339 WP_002911404.1 YebY family protein -
- 1962814..1962959 - 146 - - Antitoxin
- 1962850..1962952 + 103 - - Toxin
RJA_RS29765 1963327..1963470 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
RJA_RS09745 1963575..1964543 - 969 WP_014907334.1 VirK/YbjX family protein -
RJA_RS09750 1964700..1965353 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
RJA_RS09755 1965350..1965541 - 192 WP_002911395.1 YebW family protein -
RJA_RS09760 1965639..1965878 - 240 WP_002911393.1 YebV family protein -
RJA_RS09765 1965994..1967427 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T71594 NZ_CP019047:1962850-1962952 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT71594 NZ_CP019047:c1962959-1962814 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References