Detailed information of TA system TA071580

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yoeB-relB/YoeB-RelB
• Location: 155243..155756
• Replicon: chromosome
• Accession: NZ_CP019041
• Organism: Acinetobacter junii strain 65

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: BVL33_RS00755
• Protein ID: WP_075695918.1
• Coordinates: 155493..155756 (+)
• Length: 88 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: S7WSW9
• Locus tag: BVL33_RS00750
• Protein ID: WP_000557943.1
• Coordinates: 155243..155506 (+)
• Length: 88 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BVL33_RS00745	151480..154827	-	3348	WP_075695917.1	DEAD/DEAH box helicase	-
BVL33_RS00750	155243..155506	+	264	WP_000557943.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
BVL33_RS00755	155493..155756	+	264	WP_075695918.1	Txe/YoeB family addiction module toxin	Toxin
BVL33_RS16315	155828..155983	-	156	Protein_141	IS5/IS1182 family transposase	-
BVL33_RS00765	156194..156961	-	768	Protein_142	IS5 family transposase	-
BVL33_RS00770	157154..157327	+	174	Protein_143	VF530 family DNA-binding protein	-
BVL33_RS00775	157592..158134	-	543	Protein_144	FAD-dependent oxidoreductase	-
BVL33_RS00780	158272..158739	+	468	WP_004665270.1	Lrp/AsnC ligand binding domain-containing protein	-
BVL33_RS00785	158807..159175	-	369	WP_004907196.1	ribonuclease E inhibitor RraB	-
BVL33_RS00790	159309..159788	-	480	Protein_147	GNAT family N-acetyltransferase	-
BVL33_RS00795	159812..160435	-	624	WP_004956771.1	class I SAM-dependent methyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	104716..156961	52245
	-	flank	IS/Tn	-	-	156416..156961	545

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (8-87)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 88 a.a.
• Molecular weight: 10698.16 Da
• Isoelectric Point: 9.0274

>T71580 WP_075695918.1 NZ_CP019041:155493-155756 [Acinetobacter junii]
MTSRNVEWTENAWYEYIYWQTQDKKILKRINTLIRECQRTPFEGTGKPEPLKANLSGFWSRRIDEKHRLVYEVTDERISI
VQCRFHY

Nucleotide

• Length: 264 bp

>T71580 NZ_CP019041:155493-155756 [Acinetobacter junii]
ATGACGAGTCGTAATGTCGAATGGACTGAAAATGCCTGGTATGAATATATCTATTGGCAAACACAGGATAAAAAGATACT
CAAACGTATCAATACCTTAATCAGAGAATGTCAAAGAACACCCTTTGAAGGAACTGGAAAACCAGAACCTTTAAAAGCAA
ATCTTTCAGGATTCTGGAGCCGTAGAATTGATGAGAAGCATAGATTAGTTTATGAAGTGACGGATGAACGAATTTCCATT
GTTCAATGTCGGTTCCATTACTAA

Antitoxin

Protein

• Length: 88 a.a.
• Molecular weight: 9841.04 Da
• Isoelectric Point: 5.5940

>AT71580 WP_000557943.1 NZ_CP019041:155243-155506 [Acinetobacter junii]
MHVFTYTDARNNLKSVLDKVIDDADVAFITRKEGGHAVVMGQDHYDSLMETLYLLSSPNNTTRLNESIAQLRAGKTKQRE
LIKDDES

Nucleotide

• Length: 264 bp

>AT71580 NZ_CP019041:155243-155506 [Acinetobacter junii]
ATGCATGTATTTACATATACAGACGCACGTAACAACTTAAAATCTGTTTTAGATAAAGTTATTGATGATGCAGATGTCGC
TTTCATTACAAGAAAAGAAGGCGGTCATGCTGTAGTAATGGGACAAGATCATTACGACAGTTTAATGGAAACGTTGTATC
TCCTTTCATCTCCAAATAATACCACTCGTTTAAACGAATCAATTGCTCAATTACGCGCAGGTAAAACCAAACAAAGAGAG
TTGATTAAAGATGACGAGTCGTAA

Structures

Antitoxin

• AlphaFold DB: S7WSW9