Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4429373..4429641 Replicon chromosome
Accession NZ_CP019012
Organism Escherichia coli strain Ecol_AZ161

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4429501..4429603 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4429373..4429641 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BE946_RS24435 4425926..4426588 - 663 WP_000944256.1 exodeoxyribonuclease X -
BE946_RS24440 4426612..4427268 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
BE946_RS24445 4427370..4427600 - 231 WP_000916763.1 DNA polymerase III subunit theta -
BE946_RS24450 4427739..4428113 + 375 WP_078177588.1 CopC domain-containing protein YobA -
BE946_RS24455 4428117..4428989 + 873 WP_000879317.1 copper homeostasis membrane protein CopD -
BE946_RS24460 4429002..4429343 + 342 WP_000976472.1 YebY family protein -
- 4429373..4429641 - 269 - - Antitoxin
- 4429501..4429603 + 103 - - Toxin
BE946_RS24470 4429738..4430394 + 657 WP_000812745.1 protein-serine/threonine phosphatase -
BE946_RS24475 4430395..4430586 - 192 WP_001296140.1 YebW family protein -
BE946_RS24480 4430691..4430927 - 237 WP_001295499.1 DUF1480 family protein -
BE946_RS24485 4431044..4432483 - 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T71450 NZ_CP019012:4429501-4429603 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT71450 NZ_CP019012:c4429641-4429373 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References