Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2352998..2353266 Replicon chromosome
Accession NZ_CP019008
Organism Escherichia coli strain Ecol_AZ159

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2353126..2353228 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2352998..2353266 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BE939_RS12980 2349551..2350213 - 663 WP_000944256.1 exodeoxyribonuclease X -
BE939_RS12985 2350237..2350893 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
BE939_RS12990 2350995..2351225 - 231 WP_000916763.1 DNA polymerase III subunit theta -
BE939_RS12995 2351364..2351738 + 375 WP_000168747.1 CopC domain-containing protein YobA -
BE939_RS13000 2351742..2352614 + 873 WP_000879317.1 copper homeostasis membrane protein CopD -
BE939_RS13005 2352627..2352968 + 342 WP_000976472.1 YebY family protein -
- 2352998..2353266 - 269 - - Antitoxin
- 2353126..2353228 + 103 - - Toxin
BE939_RS13015 2353363..2354019 + 657 WP_000812745.1 protein-serine/threonine phosphatase -
BE939_RS13020 2354020..2354211 - 192 WP_001296140.1 YebW family protein -
BE939_RS13025 2354316..2354552 - 237 WP_001295499.1 DUF1480 family protein -
BE939_RS13030 2354669..2356108 - 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T71407 NZ_CP019008:2353126-2353228 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT71407 NZ_CP019008:c2353266-2352998 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References