Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2248559..2248830 Replicon chromosome
Accession NZ_CP018948
Organism Escherichia coli strain Ecol_224

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2248689..2248792 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2248559..2248830 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BE957_RS13865 2245114..2245776 - 663 WP_000944256.1 exodeoxyribonuclease X -
BE957_RS13870 2245800..2246456 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
BE957_RS13875 2246558..2246788 - 231 WP_000916763.1 DNA polymerase III subunit theta -
BE957_RS13880 2246927..2247301 + 375 WP_000204699.1 CopC domain-containing protein YobA -
BE957_RS13885 2247305..2248177 + 873 WP_000879285.1 copper homeostasis membrane protein CopD -
BE957_RS13890 2248190..2248531 + 342 WP_000976492.1 YebY family protein -
- 2248559..2248830 - 272 - - Antitoxin
- 2248689..2248792 + 104 - - Toxin
BE957_RS13895 2248927..2249583 + 657 WP_000812734.1 protein-serine/threonine phosphatase -
BE957_RS13900 2249584..2249775 - 192 WP_001296140.1 YebW family protein -
BE957_RS13905 2249880..2250116 - 237 WP_001295499.1 DUF1480 family protein -
BE957_RS13910 2250234..2251673 - 1440 WP_024190454.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T70980 NZ_CP018948:2248689-2248792 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT70980 NZ_CP018948:c2248830-2248559 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References