Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1288547..1288687 Replicon chromosome
Accession NZ_CP018930
Organism Serratia marcescens strain UMH12

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1288591..1288687 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1288547..1288687 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BVG84_RS06235 1283817..1284212 + 396 WP_049203470.1 RidA family protein -
BVG84_RS06240 1284369..1285322 + 954 WP_043141848.1 prolyl aminopeptidase -
BVG84_RS06245 1285353..1285583 - 231 WP_043141621.1 DNA polymerase III subunit theta -
BVG84_RS06250 1285928..1286446 + 519 WP_025302449.1 non-heme ferritin -
BVG84_RS06255 1286771..1287154 + 384 WP_043141618.1 CopC domain-containing protein YobA -
BVG84_RS06260 1287157..1288038 + 882 WP_060447371.1 copper homeostasis membrane protein CopD -
BVG84_RS06265 1288108..1288449 + 342 WP_025302452.1 YebY family protein -
- 1288547..1288687 - 141 - - Antitoxin
- 1288591..1288687 + 97 - - Toxin
BVG84_RS06270 1288932..1289339 + 408 WP_049204185.1 hypothetical protein -
BVG84_RS06275 1289475..1289825 + 351 WP_025302454.1 DUF4377 domain-containing protein -
BVG84_RS06280 1289864..1290700 - 837 WP_049209429.1 aminoglycoside phosphotransferase family protein -
BVG84_RS06290 1290901..1292100 + 1200 WP_025302456.1 trans-2-enoyl-CoA reductase family protein -
BVG84_RS06295 1292258..1292821 + 564 WP_025302458.1 DUF2975 domain-containing protein -
BVG84_RS06300 1292796..1293044 + 249 WP_165698098.1 helix-turn-helix transcriptional regulator -
BVG84_RS06305 1293272..1293511 + 240 WP_072008265.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 97 bp

>T70939 NZ_CP018930:1288591-1288687 [Serratia marcescens]
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 141 bp

>AT70939 NZ_CP018930:c1288687-1288547 [Serratia marcescens]
AAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TTAATGCAGGGCTTGTTCAGCCATGCACTTTAAGAGTAGCCTACCGCGCCAGTTTTGCCAG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References