Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PemK-MazE
Location 2886327..2886865 Replicon chromosome
Accession NZ_CP018911
Organism Glycocaulis alkaliphilus strain 6B-8

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag X907_RS13690 Protein ID WP_127568934.1
Coordinates 2886327..2886650 (-) Length 108 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag X907_RS13695 Protein ID WP_127568936.1
Coordinates 2886656..2886865 (-) Length 70 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
X907_RS13670 2881440..2882387 - 948 WP_127568928.1 bile acid:sodium symporter family protein -
X907_RS13675 2882538..2884280 + 1743 WP_127568930.1 M28 family peptidase -
X907_RS13680 2884405..2885358 + 954 WP_127568932.1 EamA family transporter RarD -
X907_RS13685 2885377..2886330 + 954 WP_127569540.1 alpha/beta hydrolase -
X907_RS13690 2886327..2886650 - 324 WP_127568934.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
X907_RS13695 2886656..2886865 - 210 WP_127568936.1 antitoxin MazE family protein Antitoxin
X907_RS13700 2886920..2887738 - 819 WP_127568938.1 enoyl-ACP reductase -
X907_RS13705 2888003..2888923 + 921 WP_127569542.1 acyl-CoA desaturase -
X907_RS13710 2889038..2889535 + 498 WP_127568940.1 DinB family protein -
X907_RS13715 2889511..2889924 - 414 WP_127568942.1 DUF1499 domain-containing protein -
X907_RS13720 2890061..2891008 + 948 WP_127568944.1 ATP-binding cassette domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-102)

Antitoxin

Antitoxin MazE-like

(4-67)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 11585.54 Da        Isoelectric Point: 10.3460

>T70808 WP_127568934.1 NZ_CP018911:c2886650-2886327 [Glycocaulis alkaliphilus]
VKRGDIVTVAMPGDFGKPRPALVLQADYFAQTSTVTLALISSTLVDAPLLRITLEPSEENGLRARSQIMVDKVMSVRRER
VGKVIGKADSDTLLSVNRSLVVFLGFA

Download         Length: 324 bp

>T70808 NZ_CP018911:c2886650-2886327 [Glycocaulis alkaliphilus]
GTGAAGCGCGGCGATATTGTCACCGTCGCCATGCCGGGCGATTTCGGCAAGCCGCGCCCGGCGCTGGTATTGCAGGCCGA
TTATTTCGCGCAGACCTCCACCGTAACCCTCGCCCTCATCTCTTCCACCCTGGTGGATGCGCCCTTGTTGCGGATTACGC
TGGAACCATCAGAGGAGAACGGGCTGCGTGCCCGCTCGCAGATCATGGTCGACAAGGTGATGAGCGTCCGCCGCGAGCGC
GTCGGCAAAGTCATCGGCAAGGCCGATTCCGACACGCTATTGAGCGTGAACAGGTCTTTGGTGGTGTTTCTCGGTTTCGC
CTAA

Antitoxin


Download         Length: 70 a.a.        Molecular weight: 7518.34 Da        Isoelectric Point: 4.5238

>AT70808 WP_127568936.1 NZ_CP018911:c2886865-2886656 [Glycocaulis alkaliphilus]
MGVNERVSKHREALRAAGLRPLQIWVPDTRQPGFEDACRDQAALTAEADRADAALNAFADAALADLDER

Download         Length: 210 bp

>AT70808 NZ_CP018911:c2886865-2886656 [Glycocaulis alkaliphilus]
ATGGGCGTCAATGAACGGGTCAGCAAACATCGTGAAGCCCTGCGGGCAGCGGGCCTGCGCCCCTTGCAGATTTGGGTGCC
CGATACCCGCCAGCCGGGCTTTGAAGATGCCTGCCGTGATCAAGCCGCGCTCACCGCAGAGGCAGACCGCGCCGATGCCG
CGCTGAACGCCTTCGCTGACGCGGCGCTCGCCGATCTGGACGAGCGGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References