Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-HTH_31
Location 2281275..2281890 Replicon chromosome
Accession NZ_CP018911
Organism Glycocaulis alkaliphilus strain 6B-8

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag X907_RS10825 Protein ID WP_127567876.1
Coordinates 2281639..2281890 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag X907_RS10820 Protein ID WP_127567874.1
Coordinates 2281275..2281628 (-) Length 118 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
X907_RS10795 2277254..2277805 + 552 WP_127567866.1 GDYXXLXY domain-containing protein -
X907_RS10800 2277802..2278512 - 711 WP_127567868.1 rhomboid family intramembrane serine protease -
X907_RS14455 2278612..2279154 + 543 WP_170175537.1 holdfast anchoring protein HfaA -
X907_RS10810 2279157..2280149 + 993 WP_127567870.1 holdfast anchoring protein HfaB -
X907_RS10815 2280064..2281278 + 1215 WP_127567872.1 holdfast anchor protein HfaD -
X907_RS10820 2281275..2281628 - 354 WP_127567874.1 helix-turn-helix domain-containing protein Antitoxin
X907_RS10825 2281639..2281890 - 252 WP_127567876.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
X907_RS10830 2281930..2284677 - 2748 WP_127569484.1 PQQ-binding-like beta-propeller repeat protein -
X907_RS10835 2284856..2285947 + 1092 WP_127567878.1 UDP-N-acetylglucosamine 4,6-dehydratase (inverting) -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(59-116)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9231.76 Da        Isoelectric Point: 10.5231

>T70807 WP_127567876.1 NZ_CP018911:c2281890-2281639 [Glycocaulis alkaliphilus]
VKEIAYSKQAVTALRRMPGTDARRIMAKISQFAEDPASLANNVKVLSGSPYLRLRVGDWRVIMDDQGRVLEILKIAARGG
VYE

Download         Length: 252 bp

>T70807 NZ_CP018911:c2281890-2281639 [Glycocaulis alkaliphilus]
GTGAAAGAGATTGCTTACAGCAAGCAGGCGGTAACGGCATTGCGCCGTATGCCGGGCACGGATGCACGCCGCATCATGGC
CAAGATAAGTCAGTTCGCTGAAGATCCCGCAAGCTTGGCCAATAACGTGAAGGTTCTGTCCGGATCACCTTATCTCCGCC
TGCGGGTGGGGGACTGGCGGGTCATCATGGACGATCAGGGCCGTGTACTTGAGATCCTGAAGATTGCGGCGCGAGGCGGT
GTCTATGAGTAG

Antitoxin


Download         Length: 118 a.a.        Molecular weight: 12288.10 Da        Isoelectric Point: 5.8835

>AT70807 WP_127567874.1 NZ_CP018911:c2281628-2281275 [Glycocaulis alkaliphilus]
MQTITTPSGEKLVVIPLEQYEALLDAADIAAAGKVSARVRSGEEELVPASVVAELVAGGNPVRIWRRHRGLTARTLASKA
GISPAFLSEIETGRKEGSVSALKRLAGALNVDLDDLV

Download         Length: 354 bp

>AT70807 NZ_CP018911:c2281628-2281275 [Glycocaulis alkaliphilus]
ATGCAAACCATAACCACGCCGTCCGGTGAAAAGCTGGTGGTCATTCCGCTGGAGCAGTACGAGGCGCTTCTGGACGCGGC
TGATATAGCGGCGGCCGGGAAAGTTTCGGCGCGCGTGCGCAGCGGCGAGGAAGAGCTGGTTCCGGCCAGCGTGGTCGCCG
AGCTGGTGGCTGGCGGCAATCCGGTGCGTATCTGGCGCCGTCATCGCGGACTGACGGCGCGGACGCTGGCGTCCAAGGCC
GGGATCAGCCCGGCCTTCCTGTCGGAGATCGAAACTGGACGCAAGGAGGGCAGCGTATCAGCGCTCAAGCGGCTGGCCGG
AGCGCTGAATGTCGATCTGGACGACCTGGTCTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References