Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 840834..841368 Replicon chromosome
Accession NZ_CP018911
Organism Glycocaulis alkaliphilus strain 6B-8

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag X907_RS04010 Protein ID WP_127565756.1
Coordinates 841078..841368 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag X907_RS04005 Protein ID WP_127565755.1
Coordinates 840834..841085 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
X907_RS03975 836003..836482 - 480 WP_170175453.1 GNAT family N-acetyltransferase -
X907_RS03980 836565..836777 + 213 WP_127565750.1 hypothetical protein -
X907_RS03985 836828..838525 - 1698 WP_127565751.1 MCP four helix bundle domain-containing protein -
X907_RS03990 838794..839387 - 594 WP_127565752.1 50S ribosomal protein L9 -
X907_RS03995 839399..839656 - 258 WP_127565753.1 30S ribosomal protein S18 -
X907_RS04000 839669..840019 - 351 WP_127565754.1 30S ribosomal protein S6 -
X907_RS04005 840834..841085 + 252 WP_127565755.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
X907_RS04010 841078..841368 + 291 WP_127565756.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
X907_RS04015 841453..842406 + 954 WP_127565757.1 ACP S-malonyltransferase -
X907_RS04020 842408..843145 + 738 WP_127565758.1 3-oxoacyl-[acyl-carrier-protein] reductase -
X907_RS04025 843345..843581 + 237 WP_036511926.1 acyl carrier protein -
X907_RS04030 843596..844885 + 1290 WP_127565759.1 beta-ketoacyl-ACP synthase II -
X907_RS04035 844918..845988 + 1071 WP_127565760.1 endolytic transglycosylase MltG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-90)

Antitoxin

Antitoxin ParD

(4-72)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10919.24 Da        Isoelectric Point: 4.7868

>T70803 WP_127565756.1 NZ_CP018911:841078-841368 [Glycocaulis alkaliphilus]
MAEFRLRPAARADLEGIWQDTAERWSAQQAETYISLLFDAFAALADFPLSGQDASDIREGYRQRLCGSHVIFYRPEGYGV
EIARVLQSHMLPDAHF

Download         Length: 291 bp

>T70803 NZ_CP018911:841078-841368 [Glycocaulis alkaliphilus]
ATGGCTGAATTCCGGCTGCGTCCGGCTGCACGCGCTGATCTTGAAGGCATATGGCAGGACACGGCAGAGCGCTGGTCAGC
GCAGCAGGCCGAAACCTACATCTCCCTTCTGTTCGATGCCTTTGCGGCCCTCGCCGATTTCCCGCTTTCCGGGCAGGATG
CCAGCGACATCCGCGAGGGCTATCGCCAGCGGTTGTGCGGGTCGCACGTCATCTTCTACCGGCCTGAGGGCTATGGTGTG
GAGATCGCGCGTGTGCTGCAAAGCCACATGCTGCCCGACGCGCATTTCTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 8971.02 Da        Isoelectric Point: 8.6392

>AT70803 WP_127565755.1 NZ_CP018911:840834-841085 [Glycocaulis alkaliphilus]
MSRNTSIALNDQLARYIDEQVASGRYGSASEVVRAGLRLLQEREARLSALRHALEQGEQSGPAEAVTREQFVAAMRAKAA
ANG

Download         Length: 252 bp

>AT70803 NZ_CP018911:840834-841085 [Glycocaulis alkaliphilus]
ATGAGCCGCAACACCTCCATCGCCCTGAATGACCAGCTGGCGCGCTATATCGACGAGCAGGTCGCTTCTGGCCGCTATGG
CTCTGCAAGCGAGGTCGTGCGGGCGGGACTGCGTCTTCTGCAGGAGCGTGAGGCGCGGCTGTCGGCGTTGCGGCATGCTC
TGGAGCAGGGCGAGCAGAGCGGCCCCGCCGAAGCTGTTACGCGCGAGCAGTTCGTCGCGGCGATGCGTGCCAAAGCAGCG
GCAAATGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References