Detailed information of TA system TA070800

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 3569169..3569822
• Replicon: chromosome
• Accession: NZ_CP018909
• Organism: Acinetobacter pittii strain XJ88

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: BVD86_RS17245
• Protein ID: WP_101664474.1
• Coordinates: 3569433..3569822 (+)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: A0A009HHW9
• Locus tag: BVD86_RS17240
• Protein ID: WP_002117064.1
• Coordinates: 3569169..3569426 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BVD86_RS17220	3564682..3565689	+	1008	WP_002116730.1	DNA-directed RNA polymerase subunit alpha	-
BVD86_RS17225	3565708..3566085	+	378	WP_002049717.1	50S ribosomal protein L17	-
BVD86_RS17230	3566267..3567757	+	1491	WP_101664473.1	NAD(P)/FAD-dependent oxidoreductase	-
BVD86_RS17235	3567808..3568980	-	1173	WP_014207741.1	acyl-CoA dehydrogenase family protein	-
BVD86_RS17240	3569169..3569426	+	258	WP_002117064.1	succinate dehydrogenase assembly factor 2	Antitoxin
BVD86_RS17245	3569433..3569822	+	390	WP_101664474.1	hypothetical protein	Toxin
BVD86_RS17250	3570593..3571681	+	1089	WP_014207738.1	hypothetical protein	-
BVD86_RS17255	3571766..3572341	+	576	WP_033848788.1	rhombosortase	-
BVD86_RS17260	3572521..3574716	+	2196	WP_063097833.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15519.57 Da
• Isoelectric Point: 9.1043

>T70800 WP_101664474.1 NZ_CP018909:3569433-3569822 [Acinetobacter pittii]
MIKELNFELKYSRVSLIFQLFVGLGLAILLYQLLTPIWWLYAVVLLFIGSIFFLKQAQISQIEYLDQKLWSVAYFSEKEI
YRAEITKIIDYQLFVVIYLEKTPTNIAIVWFDQLPIQQWKRLKVLEKLY

Nucleotide

• Length: 390 bp

>T70800 NZ_CP018909:3569433-3569822 [Acinetobacter pittii]
TTGATAAAAGAATTAAATTTTGAGCTGAAATATAGCCGTGTCTCGCTAATATTTCAGCTTTTTGTTGGTTTGGGTTTAGC
AATCCTGCTTTATCAGTTATTAACACCGATATGGTGGCTATATGCTGTCGTTCTTCTATTTATTGGTTCTATTTTCTTTT
TAAAGCAAGCACAAATATCTCAAATTGAATATTTAGATCAAAAATTATGGTCGGTTGCATATTTTTCGGAAAAAGAAATT
TACCGCGCGGAAATTACTAAAATAATTGATTATCAGTTATTTGTAGTTATTTATCTTGAAAAAACTCCTACGAACATAGC
TATTGTTTGGTTCGATCAGCTTCCTATTCAGCAGTGGAAAAGATTAAAAGTTTTAGAAAAGCTCTATTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10295.73 Da
• Isoelectric Point: 4.4809

>AT70800 WP_002117064.1 NZ_CP018909:3569169-3569426 [Acinetobacter pittii]
MSDEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVDQEDPDLLDWFMEVSEPPRTELREFIYKLK
QYVHG

Nucleotide

• Length: 258 bp

>AT70800 NZ_CP018909:3569169-3569426 [Acinetobacter pittii]
ATGTCTGACGAAATGACCTTGGAAGAACGTAAAGTAATTTATCGAGCACGCCGCGGCTTAAAAGAAATTGACGTCTATTT
TGACCCGTATGTAAAAAACTATTATTTAAAAGCTGATCCGGCTGAAAAAGCATTATTTGCAGAGTTGGTTGATCAAGAAG
ATCCAGATTTATTAGATTGGTTCATGGAAGTTTCTGAACCTCCACGTACTGAGTTACGTGAATTTATTTATAAACTAAAA
CAGTATGTGCATGGCTAA

Structures

Antitoxin

• AlphaFold DB: A0A009HHW9