Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 165978..166497 Replicon chromosome
Accession NZ_CP018909
Organism Acinetobacter pittii strain XJ88

Toxin (Protein)


Gene name relE Uniprot ID A0A8B5UDV5
Locus tag BVD86_RS00780 Protein ID WP_029424562.1
Coordinates 165978..166259 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A8B5UBP1
Locus tag BVD86_RS00785 Protein ID WP_029424561.1
Coordinates 166249..166497 (-) Length 83 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BVD86_RS00750 161015..162229 + 1215 WP_029424567.1 tyrosine-type recombinase/integrase -
BVD86_RS00755 162267..162647 + 381 WP_017724954.1 hypothetical protein -
BVD86_RS00760 162984..163910 + 927 WP_029424566.1 hypothetical protein -
BVD86_RS00765 163927..164136 + 210 WP_029424565.1 hypothetical protein -
BVD86_RS00770 164213..164617 - 405 WP_101663037.1 helix-turn-helix transcriptional regulator -
BVD86_RS00775 164724..165698 + 975 WP_101663038.1 hypothetical protein -
BVD86_RS00780 165978..166259 - 282 WP_029424562.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BVD86_RS00785 166249..166497 - 249 WP_029424561.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
BVD86_RS00790 166500..166904 - 405 WP_032009360.1 hypothetical protein -
BVD86_RS00795 166949..167545 - 597 WP_029424559.1 recombinase family protein -
BVD86_RS00800 167704..169128 - 1425 WP_101663039.1 hypothetical protein -
BVD86_RS00805 169186..170367 - 1182 WP_029424558.1 DUF3800 domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-83)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 94 a.a.        Molecular weight: 10843.66 Da        Isoelectric Point: 10.2259

>T70799 WP_029424562.1 NZ_CP018909:c166259-165978 [Acinetobacter pittii]
MSYNLDFLEEALEEWNKLNPSIKQPMKKKLMKVLENPRIPKNKLSGHPNRYKIKLRSVGYRLVYEVIDDEVVVLVIAVGR
RENNAIYNTAGSR

Download         Length: 282 bp

>T70799 NZ_CP018909:c166259-165978 [Acinetobacter pittii]
ATGAGCTATAACTTAGACTTTTTAGAAGAAGCATTAGAAGAATGGAATAAGCTTAATCCTAGTATTAAGCAACCAATGAA
AAAGAAACTGATGAAAGTCTTAGAGAATCCTAGAATCCCTAAGAACAAGCTATCAGGGCATCCTAACCGATATAAAATCA
AACTTCGTAGTGTTGGCTATCGTTTGGTTTATGAGGTCATAGATGATGAGGTTGTTGTATTAGTAATTGCTGTAGGCAGA
CGTGAAAATAATGCAATCTACAATACAGCAGGCTCACGATAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9272.74 Da        Isoelectric Point: 5.8061

>AT70799 WP_029424561.1 NZ_CP018909:c166497-166249 [Acinetobacter pittii]
MTQLIHARMTASITELKKSPMDTVLAGKGEAVAILNRNTPAFYCIPADLYENMIEQLEDLELNKIADTRANQKRIRVNIN
EL

Download         Length: 249 bp

>AT70799 NZ_CP018909:c166497-166249 [Acinetobacter pittii]
ATGACTCAACTAATCCATGCACGAATGACTGCAAGTATTACTGAACTCAAAAAGAGTCCTATGGATACTGTATTAGCAGG
TAAAGGTGAAGCTGTTGCTATTCTTAACCGTAATACCCCTGCTTTCTACTGTATTCCTGCTGATCTATATGAAAATATGA
TTGAACAGCTAGAGGACTTAGAACTCAATAAAATTGCAGATACTCGTGCGAATCAAAAGCGTATTCGAGTAAACATAAAT
GAGCTATAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A8B5UDV5


Antitoxin

Source ID Structure
AlphaFold DB A0A8B5UBP1

References