Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/ParE-YafN |
Location | 165978..166497 | Replicon | chromosome |
Accession | NZ_CP018909 | ||
Organism | Acinetobacter pittii strain XJ88 |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A8B5UDV5 |
Locus tag | BVD86_RS00780 | Protein ID | WP_029424562.1 |
Coordinates | 165978..166259 (-) | Length | 94 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | A0A8B5UBP1 |
Locus tag | BVD86_RS00785 | Protein ID | WP_029424561.1 |
Coordinates | 166249..166497 (-) | Length | 83 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BVD86_RS00750 | 161015..162229 | + | 1215 | WP_029424567.1 | tyrosine-type recombinase/integrase | - |
BVD86_RS00755 | 162267..162647 | + | 381 | WP_017724954.1 | hypothetical protein | - |
BVD86_RS00760 | 162984..163910 | + | 927 | WP_029424566.1 | hypothetical protein | - |
BVD86_RS00765 | 163927..164136 | + | 210 | WP_029424565.1 | hypothetical protein | - |
BVD86_RS00770 | 164213..164617 | - | 405 | WP_101663037.1 | helix-turn-helix transcriptional regulator | - |
BVD86_RS00775 | 164724..165698 | + | 975 | WP_101663038.1 | hypothetical protein | - |
BVD86_RS00780 | 165978..166259 | - | 282 | WP_029424562.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
BVD86_RS00785 | 166249..166497 | - | 249 | WP_029424561.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
BVD86_RS00790 | 166500..166904 | - | 405 | WP_032009360.1 | hypothetical protein | - |
BVD86_RS00795 | 166949..167545 | - | 597 | WP_029424559.1 | recombinase family protein | - |
BVD86_RS00800 | 167704..169128 | - | 1425 | WP_101663039.1 | hypothetical protein | - |
BVD86_RS00805 | 169186..170367 | - | 1182 | WP_029424558.1 | DUF3800 domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 94 a.a. Molecular weight: 10843.66 Da Isoelectric Point: 10.2259
>T70799 WP_029424562.1 NZ_CP018909:c166259-165978 [Acinetobacter pittii]
MSYNLDFLEEALEEWNKLNPSIKQPMKKKLMKVLENPRIPKNKLSGHPNRYKIKLRSVGYRLVYEVIDDEVVVLVIAVGR
RENNAIYNTAGSR
MSYNLDFLEEALEEWNKLNPSIKQPMKKKLMKVLENPRIPKNKLSGHPNRYKIKLRSVGYRLVYEVIDDEVVVLVIAVGR
RENNAIYNTAGSR
Download Length: 282 bp
>T70799 NZ_CP018909:c166259-165978 [Acinetobacter pittii]
ATGAGCTATAACTTAGACTTTTTAGAAGAAGCATTAGAAGAATGGAATAAGCTTAATCCTAGTATTAAGCAACCAATGAA
AAAGAAACTGATGAAAGTCTTAGAGAATCCTAGAATCCCTAAGAACAAGCTATCAGGGCATCCTAACCGATATAAAATCA
AACTTCGTAGTGTTGGCTATCGTTTGGTTTATGAGGTCATAGATGATGAGGTTGTTGTATTAGTAATTGCTGTAGGCAGA
CGTGAAAATAATGCAATCTACAATACAGCAGGCTCACGATAA
ATGAGCTATAACTTAGACTTTTTAGAAGAAGCATTAGAAGAATGGAATAAGCTTAATCCTAGTATTAAGCAACCAATGAA
AAAGAAACTGATGAAAGTCTTAGAGAATCCTAGAATCCCTAAGAACAAGCTATCAGGGCATCCTAACCGATATAAAATCA
AACTTCGTAGTGTTGGCTATCGTTTGGTTTATGAGGTCATAGATGATGAGGTTGTTGTATTAGTAATTGCTGTAGGCAGA
CGTGAAAATAATGCAATCTACAATACAGCAGGCTCACGATAA
Antitoxin
Download Length: 83 a.a. Molecular weight: 9272.74 Da Isoelectric Point: 5.8061
>AT70799 WP_029424561.1 NZ_CP018909:c166497-166249 [Acinetobacter pittii]
MTQLIHARMTASITELKKSPMDTVLAGKGEAVAILNRNTPAFYCIPADLYENMIEQLEDLELNKIADTRANQKRIRVNIN
EL
MTQLIHARMTASITELKKSPMDTVLAGKGEAVAILNRNTPAFYCIPADLYENMIEQLEDLELNKIADTRANQKRIRVNIN
EL
Download Length: 249 bp
>AT70799 NZ_CP018909:c166497-166249 [Acinetobacter pittii]
ATGACTCAACTAATCCATGCACGAATGACTGCAAGTATTACTGAACTCAAAAAGAGTCCTATGGATACTGTATTAGCAGG
TAAAGGTGAAGCTGTTGCTATTCTTAACCGTAATACCCCTGCTTTCTACTGTATTCCTGCTGATCTATATGAAAATATGA
TTGAACAGCTAGAGGACTTAGAACTCAATAAAATTGCAGATACTCGTGCGAATCAAAAGCGTATTCGAGTAAACATAAAT
GAGCTATAA
ATGACTCAACTAATCCATGCACGAATGACTGCAAGTATTACTGAACTCAAAAAGAGTCCTATGGATACTGTATTAGCAGG
TAAAGGTGAAGCTGTTGCTATTCTTAACCGTAATACCCCTGCTTTCTACTGTATTCCTGCTGATCTATATGAAAATATGA
TTGAACAGCTAGAGGACTTAGAACTCAATAAAATTGCAGATACTCGTGCGAATCAAAAGCGTATTCGAGTAAACATAAAT
GAGCTATAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A8B5UDV5 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A8B5UBP1 |