Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 4823376..4823521 | Replicon | chromosome |
| Accession | NZ_CP018885 | ||
| Organism | Klebsiella pneumoniae subsp. pneumoniae strain BR21 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 4823383..4823485 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 4823376..4823521 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BU813_RS24690 | 4818907..4820340 | + | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| BU813_RS24695 | 4820456..4820695 | + | 240 | WP_002911393.1 | YebV family protein | - |
| BU813_RS24700 | 4820793..4820984 | + | 192 | WP_002911395.1 | YebW family protein | - |
| BU813_RS24705 | 4820981..4821634 | - | 654 | WP_032441330.1 | protein-serine/threonine phosphatase | - |
| BU813_RS24710 | 4821791..4822759 | + | 969 | WP_073971755.1 | VirK/YbjX family protein | - |
| BU813_RS29510 | 4822864..4823007 | + | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| - | 4823376..4823521 | + | 146 | - | - | Antitoxin |
| - | 4823383..4823485 | - | 103 | - | - | Toxin |
| BU813_RS24720 | 4823644..4823982 | - | 339 | WP_002911404.1 | YebY family protein | - |
| BU813_RS24725 | 4823999..4824868 | - | 870 | WP_004189267.1 | copper homeostasis membrane protein CopD | - |
| BU813_RS24730 | 4824872..4825246 | - | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| BU813_RS24735 | 4825359..4825589 | + | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| BU813_RS24740 | 4825668..4826327 | + | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| BU813_RS24745 | 4826331..4828391 | - | 2061 | WP_004151449.1 | oligopeptidase B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T70766 NZ_CP018885:c4823485-4823383 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT70766 NZ_CP018885:4823376-4823521 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT