Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4823376..4823521 Replicon chromosome
Accession NZ_CP018885
Organism Klebsiella pneumoniae subsp. pneumoniae strain BR21

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4823383..4823485 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4823376..4823521 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BU813_RS24690 4818907..4820340 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
BU813_RS24695 4820456..4820695 + 240 WP_002911393.1 YebV family protein -
BU813_RS24700 4820793..4820984 + 192 WP_002911395.1 YebW family protein -
BU813_RS24705 4820981..4821634 - 654 WP_032441330.1 protein-serine/threonine phosphatase -
BU813_RS24710 4821791..4822759 + 969 WP_073971755.1 VirK/YbjX family protein -
BU813_RS29510 4822864..4823007 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 4823376..4823521 + 146 - - Antitoxin
- 4823383..4823485 - 103 - - Toxin
BU813_RS24720 4823644..4823982 - 339 WP_002911404.1 YebY family protein -
BU813_RS24725 4823999..4824868 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
BU813_RS24730 4824872..4825246 - 375 WP_004151448.1 CopC domain-containing protein YobA -
BU813_RS24735 4825359..4825589 + 231 WP_002911406.1 DNA polymerase III subunit theta -
BU813_RS24740 4825668..4826327 + 660 WP_002911407.1 exodeoxyribonuclease X -
BU813_RS24745 4826331..4828391 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T70766 NZ_CP018885:c4823485-4823383 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT70766 NZ_CP018885:4823376-4823521 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References