Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 446345..446984 Replicon chromosome
Accession NZ_CP018871
Organism Acinetobacter haemolyticus strain TJS01

Toxin (Protein)


Gene name cptA Uniprot ID C0VNL5
Locus tag AHTJS_RS02230 Protein ID WP_005088316.1
Coordinates 446589..446984 (+) Length 132 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID N9FB90
Locus tag AHTJS_RS02225 Protein ID WP_004641025.1
Coordinates 446345..446602 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AHTJS_RS02200 441423..441788 + 366 WP_004641032.1 50S ribosomal protein L17 -
AHTJS_RS02205 441949..442446 + 498 WP_075316485.1 GNAT family N-acetyltransferase -
AHTJS_RS02210 442824..444314 + 1491 WP_075314692.1 NAD(P)/FAD-dependent oxidoreductase -
AHTJS_RS02215 444437..444934 + 498 WP_005088321.1 DUF2059 domain-containing protein -
AHTJS_RS02220 444986..446158 - 1173 WP_005086825.1 acyl-CoA dehydrogenase family protein -
AHTJS_RS02225 446345..446602 + 258 WP_004641025.1 succinate dehydrogenase assembly factor 2 Antitoxin
AHTJS_RS02230 446589..446984 + 396 WP_005088316.1 hypothetical protein Toxin
AHTJS_RS02235 447195..447401 + 207 WP_171261742.1 hypothetical protein -
AHTJS_RS02240 447761..448804 + 1044 WP_075314696.1 hypothetical protein -
AHTJS_RS02245 448932..449513 + 582 WP_004641018.1 rhombosortase -
AHTJS_RS02250 449691..451901 + 2211 WP_004641016.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 16153.44 Da        Isoelectric Point: 9.1954

>T70733 WP_005088316.1 NZ_CP018871:446589-446984 [Acinetobacter haemolyticus]
MSTADRVFVLKRSRFAFAFQLFIFIVLISLLYYLLPWFLWLVSFPLMLIAWVLLLKQPQLKHFEYLDDQLCSLCFSDEMQ
RIEQRKIRKMIDHQCYIVIYFYDSQCRPCVIWWDQLSILQWKKLRTWVKLA

Download         Length: 396 bp

>T70733 NZ_CP018871:446589-446984 [Acinetobacter haemolyticus]
ATGTCCACGGCTGATCGTGTTTTTGTGTTGAAACGCAGTCGTTTTGCATTTGCGTTTCAACTTTTTATTTTTATCGTACT
GATCAGTTTATTGTATTACTTACTTCCTTGGTTTTTATGGCTTGTTAGCTTTCCTTTGATGCTAATTGCTTGGGTATTAT
TACTCAAACAACCTCAGCTTAAACACTTTGAATATTTAGATGATCAGCTTTGCTCCTTGTGTTTTAGTGATGAGATGCAG
AGGATCGAGCAAAGGAAAATTCGAAAAATGATCGATCATCAATGTTATATCGTCATCTATTTTTATGACTCTCAATGTCG
ACCTTGTGTGATTTGGTGGGATCAATTGTCGATTTTACAGTGGAAAAAGCTCAGAACATGGGTCAAACTTGCATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9982.42 Da        Isoelectric Point: 4.4558

>AT70733 WP_004641025.1 NZ_CP018871:446345-446602 [Acinetobacter haemolyticus]
MSEELTLEERKVIYRARRGLKEIDVYFDPYVKNCYLTADAAEKALFAELVDQEDPDLLDWFMEVGEPPRPELKAFISKLK
QYVHG

Download         Length: 258 bp

>AT70733 NZ_CP018871:446345-446602 [Acinetobacter haemolyticus]
ATGTCTGAAGAATTGACACTAGAAGAACGTAAAGTGATTTATCGTGCGCGTCGTGGTTTGAAAGAAATCGATGTGTATTT
TGATCCTTATGTTAAAAATTGTTATCTCACAGCAGATGCGGCTGAGAAAGCATTGTTTGCAGAGTTGGTAGATCAAGAAG
ATCCTGATTTACTGGATTGGTTCATGGAGGTGGGTGAACCTCCTCGTCCAGAGTTAAAAGCGTTTATTTCAAAATTAAAA
CAGTATGTCCACGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1L6KJV0

Antitoxin

Source ID Structure
AlphaFold DB N9FB90

References