Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 305043..305702 Replicon chromosome
Accession NZ_CP018871
Organism Acinetobacter haemolyticus strain TJS01

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag AHTJS_RS01440 Protein ID WP_008941148.1
Coordinates 305292..305702 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag AHTJS_RS01435 Protein ID WP_167365846.1
Coordinates 305043..305291 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AHTJS_RS01405 301089..301301 + 213 WP_017395601.1 addiction module protein -
AHTJS_RS01410 301298..301576 + 279 WP_075314557.1 type II toxin-antitoxin system RelE/ParE family toxin -
AHTJS_RS01415 301715..302605 + 891 WP_075314559.1 metal-dependent hydrolase -
AHTJS_RS01420 302779..303369 + 591 WP_004641306.1 LemA family protein -
AHTJS_RS01425 303394..304455 + 1062 WP_075314561.1 TPM domain-containing protein -
AHTJS_RS01430 304449..305009 + 561 WP_075314563.1 TPM domain-containing protein -
AHTJS_RS01435 305043..305291 + 249 WP_167365846.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
AHTJS_RS01440 305292..305702 + 411 WP_008941148.1 tRNA(fMet)-specific endonuclease VapC Toxin
AHTJS_RS01445 305852..307042 + 1191 WP_075314564.1 Fic family protein -
AHTJS_RS01450 307508..308020 + 513 Protein_270 hypothetical protein -
AHTJS_RS01455 308339..308698 + 360 WP_005018086.1 DUF2384 domain-containing protein -
AHTJS_RS01460 308797..309582 + 786 WP_075314566.1 hypothetical protein -
AHTJS_RS01465 309614..310090 - 477 Protein_273 HAD-IA family hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15384.81 Da        Isoelectric Point: 8.8849

>T70732 WP_008941148.1 NZ_CP018871:305292-305702 [Acinetobacter haemolyticus]
MLKYMLDTNIVIYTIKQRPLAVKERFNAVSTQLCISSITVAELIFGAENSQMPEKNLKVVEDFLSRLQILDYGVDAAIQY
GNIKAQLKRKGQPIGENDLHIAAHARSRGLILVTNNTREFERVPALQIENWLKESG

Download         Length: 411 bp

>T70732 NZ_CP018871:305292-305702 [Acinetobacter haemolyticus]
ATGCTGAAATATATGCTTGATACCAATATTGTGATTTATACAATAAAACAAAGACCACTGGCGGTTAAAGAAAGGTTTAA
TGCTGTTTCAACACAACTTTGTATCAGTAGTATCACTGTTGCGGAATTAATTTTTGGGGCGGAAAATAGCCAAATGCCCG
AGAAGAATTTAAAAGTTGTAGAGGATTTTTTATCACGATTGCAAATTTTGGATTATGGCGTAGATGCTGCAATCCAATAT
GGAAATATTAAAGCTCAGCTAAAAAGAAAAGGTCAACCGATTGGCGAGAATGATCTACATATCGCAGCTCATGCGAGAAG
TAGGGGATTGATTTTGGTGACCAATAATACAAGAGAGTTTGAGCGTGTGCCTGCACTACAGATAGAAAACTGGTTGAAAG
AAAGCGGTTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9561.75 Da        Isoelectric Point: 4.5843

>AT70732 WP_167365846.1 NZ_CP018871:305043-305291 [Acinetobacter haemolyticus]
MARGRCAVITTVFMNNRTQAVRLPSIYRFSETTQKVFVRQVGVERVISPVEQVWDSFFEDPELQLSDDFERGEQISAERE
SF

Download         Length: 249 bp

>AT70732 NZ_CP018871:305043-305291 [Acinetobacter haemolyticus]
ATGGCGAGAGGGAGGTGTGCTGTGATTACAACCGTATTTATGAATAATCGTACCCAAGCAGTAAGACTACCGAGTATTTA
TCGTTTTTCTGAAACAACTCAAAAAGTTTTTGTGCGACAGGTGGGGGTTGAGCGAGTGATTAGCCCAGTAGAACAGGTTT
GGGATAGTTTTTTCGAAGATCCTGAGTTACAACTTTCAGATGACTTTGAGCGTGGCGAACAAATTTCAGCAGAGAGAGAG
TCGTTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References