70723

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4123177..4123538 Replicon chromosome
Accession NZ_CP018858
Organism Xanthomonas citri pv. citri strain LH201

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag BJD09_RS18655 Protein ID WP_005914328.1
Coordinates 4123404..4123538 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag BJD09_RS18650 Protein ID WP_003486606.1
Coordinates 4123177..4123329 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJD09_RS18615 4118277..4118960 - 684 WP_011052674.1 dTMP kinase -
BJD09_RS18625 4119398..4119940 - 543 WP_003486615.1 GTPase -
BJD09_RS18630 4119937..4120854 - 918 WP_011052673.1 hypothetical protein -
BJD09_RS18635 4120951..4121310 - 360 WP_003486613.1 hypothetical protein -
BJD09_RS18640 4121374..4121826 - 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
BJD09_RS18645 4122147..4123070 + 924 WP_005927745.1 arginase -
BJD09_RS18650 4123177..4123329 + 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
BJD09_RS18655 4123404..4123538 + 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
BJD09_RS18660 4123765..4123974 + 210 WP_003486601.1 CsbD family protein -
BJD09_RS18665 4124155..4125444 + 1290 WP_015463705.1 tryptophan--tRNA ligase -
BJD09_RS18670 4125483..4126352 + 870 Protein_3456 MBL fold metallo-hydrolase -
BJD09_RS18675 4126355..4128046 + 1692 WP_015471463.1 M20/M25/M40 family metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T70723 WP_005914328.1 NZ_CP018858:4123404-4123538 [Xanthomonas citri pv. citri]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T70723 NZ_CP018858:4123404-4123538 [Xanthomonas citri pv. citri]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT70723 WP_003486606.1 NZ_CP018858:4123177-4123329 [Xanthomonas citri pv. citri]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT70723 NZ_CP018858:4123177-4123329 [Xanthomonas citri pv. citri]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References