Detailed information of TA system TA070720

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/PIN-MazE
• Location: 1069501..1070134
• Replicon: chromosome
• Accession: NZ_CP018858
• Organism: Xanthomonas citri pv. citri strain LH201

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: BJD09_RS04820
• Protein ID: WP_015463212.1
• Coordinates: 1069721..1070134 (+)
• Length: 138 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: M4TWF0
• Locus tag: BJD09_RS04815
• Protein ID: WP_015463213.1
• Coordinates: 1069501..1069734 (+)
• Length: 78 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BJD09_RS04795	1065624..1066673	-	1050	WP_011051401.1	FecR domain-containing protein	-
BJD09_RS04800	1066654..1067229	-	576	WP_011051400.1	sigma-70 family RNA polymerase sigma factor	-
BJD09_RS04805	1067681..1068079	+	399	WP_099521978.1	hypothetical protein	-
BJD09_RS04810	1068212..1069243	-	1032	WP_040107627.1	DUF4917 family protein	-
BJD09_RS04815	1069501..1069734	+	234	WP_015463213.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
BJD09_RS04820	1069721..1070134	+	414	WP_015463212.1	PIN domain-containing protein	Toxin
BJD09_RS04825	1070161..1070523	+	363	WP_015463211.1	DUF3742 family protein	-
BJD09_RS04830	1070539..1072053	-	1515	WP_015463210.1	conjugal transfer protein TraG N-terminal domain-containing protein	-
BJD09_RS04835	1072262..1074442	-	2181	WP_011051394.1	TonB-dependent siderophore receptor	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1061937..1082640	20703

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (8-119)

Antitoxin

• SpoVT-AbrB domain (5-45)

Sequences

Toxin

Protein

• Length: 138 a.a.
• Molecular weight: 15221.65 Da
• Isoelectric Point: 6.3225

>T70720 WP_015463212.1 NZ_CP018858:1069721-1070134 [Xanthomonas citri pv. citri]
MAAGKGKVFLDSNVVLYLLSEDAVKADGAEALLQRRPVISVQVLNEVTHVCVRKLKMGWDEVGQFLALVRSFCKIVPLTV
DVHDRARQLAERHQLSFYDACIVAAAAIEGCQTLYSEDMHHGLIIEESLSIRNPFNV

Nucleotide

• Length: 414 bp

>T70720 NZ_CP018858:1069721-1070134 [Xanthomonas citri pv. citri]
ATGGCCGCGGGTAAGGGCAAAGTGTTTCTCGACAGCAACGTGGTGCTCTACCTGCTGTCGGAGGATGCGGTGAAGGCGGA
CGGCGCGGAGGCATTGCTGCAGCGCAGGCCCGTCATCAGTGTGCAGGTGCTCAATGAAGTGACCCACGTCTGCGTTCGCA
AGCTCAAGATGGGCTGGGACGAAGTCGGGCAGTTCCTTGCGTTGGTGCGATCGTTCTGCAAGATAGTGCCTCTGACGGTC
GATGTTCACGACCGTGCGCGCCAGCTGGCGGAGCGGCACCAATTGTCGTTCTACGACGCGTGCATCGTGGCGGCGGCCGC
CATCGAAGGGTGCCAGACCCTCTACTCCGAAGACATGCACCACGGCCTCATCATCGAAGAGAGCCTGTCGATTCGGAACC
CGTTCAACGTCTGA

Antitoxin

Protein

• Length: 78 a.a.
• Molecular weight: 8663.97 Da
• Isoelectric Point: 8.7848

>AT70720 WP_015463213.1 NZ_CP018858:1069501-1069734 [Xanthomonas citri pv. citri]
MQVAKWGNSLAVRLPSSLVEALELREGDDIEIVVDDPRLFAVRKKPGPEAMLERLRAFRGKLPADFKFNRDEANGRG

Nucleotide

• Length: 234 bp

>AT70720 NZ_CP018858:1069501-1069734 [Xanthomonas citri pv. citri]
ATGCAAGTCGCGAAGTGGGGTAACAGCCTGGCGGTGCGCCTGCCGTCCAGTCTGGTGGAAGCGCTGGAACTGCGCGAGGG
CGACGACATCGAGATCGTCGTCGATGATCCGCGATTGTTCGCGGTGCGCAAGAAGCCGGGTCCGGAGGCCATGTTGGAGC
GGCTGCGTGCCTTCCGGGGCAAGTTGCCCGCAGATTTCAAGTTCAACCGGGACGAGGCCAATGGCCGCGGGTAA

Structures

Antitoxin

• AlphaFold DB: M4TWF0