70715

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4998867..4999228 Replicon chromosome
Accession NZ_CP018854
Organism Xanthomonas citri pv. citri strain LH276

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag BI316_RS22630 Protein ID WP_005914328.1
Coordinates 4998867..4999001 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag BI316_RS22635 Protein ID WP_003486606.1
Coordinates 4999076..4999228 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BI316_RS22610 4994359..4996050 - 1692 WP_015471463.1 M20/M25/M40 family metallo-hydrolase -
BI316_RS22615 4996053..4996922 - 870 Protein_4176 MBL fold metallo-hydrolase -
BI316_RS22620 4996961..4998250 - 1290 WP_015463705.1 tryptophan--tRNA ligase -
BI316_RS22625 4998431..4998640 - 210 WP_003486601.1 CsbD family protein -
BI316_RS22630 4998867..4999001 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
BI316_RS22635 4999076..4999228 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
BI316_RS22640 4999335..5000258 - 924 WP_005927745.1 arginase -
BI316_RS22645 5000579..5001031 + 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
BI316_RS22650 5001095..5001454 + 360 WP_003486613.1 hypothetical protein -
BI316_RS22655 5001551..5002468 + 918 WP_011052673.1 hypothetical protein -
BI316_RS22660 5002465..5003007 + 543 WP_003486615.1 GTPase -
BI316_RS22670 5003445..5004128 + 684 WP_011052674.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T70715 WP_005914328.1 NZ_CP018854:c4999001-4998867 [Xanthomonas citri pv. citri]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T70715 NZ_CP018854:c4999001-4998867 [Xanthomonas citri pv. citri]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT70715 WP_003486606.1 NZ_CP018854:c4999228-4999076 [Xanthomonas citri pv. citri]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT70715 NZ_CP018854:c4999228-4999076 [Xanthomonas citri pv. citri]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References