Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 2508928..2509289 Replicon chromosome
Accession NZ_CP018850
Organism Xanthomonas citri pv. citri strain LJ207-7

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag BI315_RS11250 Protein ID WP_005914328.1
Coordinates 2508928..2509062 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag BI315_RS11255 Protein ID WP_003486606.1
Coordinates 2509137..2509289 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BI315_RS11230 2504066..2505757 - 1692 WP_015471463.1 M20/M25/M40 family metallo-hydrolase -
BI315_RS11235 2505949..2506983 - 1035 WP_011052671.1 MBL fold metallo-hydrolase -
BI315_RS11240 2507022..2508311 - 1290 WP_015463705.1 tryptophan--tRNA ligase -
BI315_RS11245 2508492..2508701 - 210 WP_003486601.1 CsbD family protein -
BI315_RS11250 2508928..2509062 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
BI315_RS11255 2509137..2509289 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
BI315_RS11260 2509396..2510319 - 924 WP_005927745.1 arginase -
BI315_RS11265 2510640..2511092 + 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
BI315_RS11270 2511156..2511515 + 360 WP_003486613.1 hypothetical protein -
BI315_RS11275 2511612..2512529 + 918 WP_011052673.1 hypothetical protein -
BI315_RS11280 2512526..2513068 + 543 WP_003486615.1 GTPase -
BI315_RS11290 2513506..2514189 + 684 WP_011052674.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T70705 WP_005914328.1 NZ_CP018850:c2509062-2508928 [Xanthomonas citri pv. citri]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T70705 NZ_CP018850:c2509062-2508928 [Xanthomonas citri pv. citri]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT70705 WP_003486606.1 NZ_CP018850:c2509289-2509137 [Xanthomonas citri pv. citri]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT70705 NZ_CP018850:c2509289-2509137 [Xanthomonas citri pv. citri]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References