Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | EcnAB/- |
Location | 827055..827416 | Replicon | chromosome |
Accession | NZ_CP018847 | ||
Organism | Xanthomonas citri pv. citri strain LL074-4 |
Toxin (Protein)
Gene name | EcnB | Uniprot ID | M4UGA1 |
Locus tag | BI314_RS03660 | Protein ID | WP_005914328.1 |
Coordinates | 827282..827416 (+) | Length | 45 a.a. |
Antitoxin (Protein)
Gene name | EcnA | Uniprot ID | H8FG64 |
Locus tag | BI314_RS03655 | Protein ID | WP_003486606.1 |
Coordinates | 827055..827207 (+) | Length | 51 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BI314_RS03620 | 822155..822838 | - | 684 | WP_011052674.1 | dTMP kinase | - |
BI314_RS03630 | 823276..823818 | - | 543 | WP_003486615.1 | GTPase | - |
BI314_RS03635 | 823815..824732 | - | 918 | WP_011052673.1 | hypothetical protein | - |
BI314_RS03640 | 824829..825188 | - | 360 | WP_003486613.1 | hypothetical protein | - |
BI314_RS03645 | 825252..825704 | - | 453 | WP_003486611.1 | roadblock/LC7 domain-containing protein | - |
BI314_RS03650 | 826025..826948 | + | 924 | WP_005927745.1 | arginase | - |
BI314_RS03655 | 827055..827207 | + | 153 | WP_003486606.1 | entericidin A/B family lipoprotein | Antitoxin |
BI314_RS03660 | 827282..827416 | + | 135 | WP_005914328.1 | entericidin A/B family lipoprotein | Toxin |
BI314_RS03665 | 827643..827852 | + | 210 | WP_003486601.1 | CsbD family protein | - |
BI314_RS03670 | 828033..829322 | + | 1290 | WP_015463705.1 | tryptophan--tRNA ligase | - |
BI314_RS03675 | 829361..830230 | + | 870 | Protein_667 | MBL fold metallo-hydrolase | - |
BI314_RS03680 | 830233..831924 | + | 1692 | WP_015471463.1 | M20/M25/M40 family metallo-hydrolase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 45 a.a. Molecular weight: 4459.32 Da Isoelectric Point: 9.3487
>T70698 WP_005914328.1 NZ_CP018847:827282-827416 [Xanthomonas citri pv. citri]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK
Download Length: 135 bp
>T70698 NZ_CP018847:827282-827416 [Xanthomonas citri pv. citri]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA
Antitoxin
Download Length: 51 a.a. Molecular weight: 5122.07 Da Isoelectric Point: 8.7942
>AT70698 WP_003486606.1 NZ_CP018847:827055-827207 [Xanthomonas citri pv. citri]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC
Download Length: 153 bp
>AT70698 NZ_CP018847:827055-827207 [Xanthomonas citri pv. citri]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3G2W7U6 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A828YLX6 |