70698

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 827055..827416 Replicon chromosome
Accession NZ_CP018847
Organism Xanthomonas citri pv. citri strain LL074-4

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag BI314_RS03660 Protein ID WP_005914328.1
Coordinates 827282..827416 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag BI314_RS03655 Protein ID WP_003486606.1
Coordinates 827055..827207 (+) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BI314_RS03620 822155..822838 - 684 WP_011052674.1 dTMP kinase -
BI314_RS03630 823276..823818 - 543 WP_003486615.1 GTPase -
BI314_RS03635 823815..824732 - 918 WP_011052673.1 hypothetical protein -
BI314_RS03640 824829..825188 - 360 WP_003486613.1 hypothetical protein -
BI314_RS03645 825252..825704 - 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
BI314_RS03650 826025..826948 + 924 WP_005927745.1 arginase -
BI314_RS03655 827055..827207 + 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
BI314_RS03660 827282..827416 + 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
BI314_RS03665 827643..827852 + 210 WP_003486601.1 CsbD family protein -
BI314_RS03670 828033..829322 + 1290 WP_015463705.1 tryptophan--tRNA ligase -
BI314_RS03675 829361..830230 + 870 Protein_667 MBL fold metallo-hydrolase -
BI314_RS03680 830233..831924 + 1692 WP_015471463.1 M20/M25/M40 family metallo-hydrolase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T70698 WP_005914328.1 NZ_CP018847:827282-827416 [Xanthomonas citri pv. citri]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T70698 NZ_CP018847:827282-827416 [Xanthomonas citri pv. citri]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT70698 WP_003486606.1 NZ_CP018847:827055-827207 [Xanthomonas citri pv. citri]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT70698 NZ_CP018847:827055-827207 [Xanthomonas citri pv. citri]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6


Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References